About: The secretome of facultative intracelullar bacterium Francisella tularensis

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Sekretom fakultativně intracelulární bakterie Francisella tularensis. (cs) The gram negative coccobacillus, Francisella tularensis, is a facultative intracellular bacterial pathogen which naturally causes the zoonotic disease tularemia.Recently, Francisella pathogenicity island (FPI) encoding several genes required for both intracellular survival in macrophages and virulence in the mouse infection model was described (Nano et al., 2004). Furthermore, gene clusters encoding proteins required for either a type I (transporters containing ATP-binding casettes) or a type II secretion systems (type IV pili system) were detected in F. tularensis genome. The key factor for the survival the bacterium in hostile intracellular milieu is then its ability of iron acquisition. From this point of view Fur protein and a number of genes that may be regulated by Fur were predicted in genome of F. tularensis SCHU S4. The aim of this work is the analysis of alteration of culture filtrate protein patterns of Francisella tularensis subsp. holarctica strain LVS induced by iron restriction. The gram negative coccobacillus, Francisella tularensis, is a facultative intracellular bacterial pathogen which naturally causes the zoonotic disease tularemia.Recently, Francisella pathogenicity island (FPI) encoding several genes required for both intracellular survival in macrophages and virulence in the mouse infection model was described (Nano et al., 2004). Furthermore, gene clusters encoding proteins required for either a type I (transporters containing ATP-binding casettes) or a type II secretion systems (type IV pili system) were detected in F. tularensis genome. The key factor for the survival the bacterium in hostile intracellular milieu is then its ability of iron acquisition. From this point of view Fur protein and a number of genes that may be regulated by Fur were predicted in genome of F. tularensis SCHU S4. The aim of this work is the analysis of alteration of culture filtrate protein patterns of Francisella tularensis subsp. holarctica strain LVS induced by iron restriction. (en)
Title	The secretome of facultative intracelullar bacterium Francisella tularensis The secretome of facultative intracelullar bacterium Francisella tularensis (en) Sekretom fakultativně intracelulární bakterie Francisella tularensis (cs)
skos:prefLabel	The secretome of facultative intracelullar bacterium Francisella tularensis The secretome of facultative intracelullar bacterium Francisella tularensis (en) Sekretom fakultativně intracelulární bakterie Francisella tularensis (cs)
skos:notation	RIV/60162694:G44__/05:00001388!RIV06-MO0-G44_____
http://linked.open.../vavai/riv/strany	77-81
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(OBVLAJEP20031), P(OBVLAJEP20033)
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Hernychová, Lenka
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	542067
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/05:00001388
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Francisella tularensis; Chamberlain medium; mass spectrometry (en)
http://linked.open.../riv/klicoveSlovo	mass spectrometry Francisella tularensis Chamberlain medium
http://linked.open...ontrolniKodProRIV	[A29C023C451A]
http://linked.open...v/mistoKonaniAkce	Hradec Králové
http://linked.open...i/riv/mistoVydani	Hradec Králové
http://linked.open...i/riv/nazevZdroje	New frontiers in the research of PhD students, Conference of Medical Schools in the Czech and Slovak Republics
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	AB-AGENTS - Continuation of the medical problem of protection against A and B agent research INFECTION 2 - The use of proteome analysis in microbiological diagnostics of infections whose aetiological agentsare on the listof BW-agents
http://linked.open...UplatneniVysledku	2005
http://linked.open...iv/tvurceVysledku	Hernychová, Lenka Šlosrová, K.
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2005-12-09 (xsd:date)
number of pages	5 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Astraprint
https://schema.org/isbn	80-239-6102-0
http://localhost/t...ganizacniJednotka	G44

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