About: In vitro reactivation potency of some acetylcholinesterase reactivators against sarin and cyclosarin-induced inhibitions     Goto   Sponge   NotDistinct   Permalink

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  • In our study, we have tested six acetylcholinesterase (AChE) reactivators - pralidoxime, obidoxime, HI-6, trimedoxime, BI-6, and Hlö-7 - for reactivation of sarin and cyclosarin inhibited AChE using an in vitro reactivation test. We have used rat brain homogenate as the suitable source of enzyme. All oximes are able to reactivate sarin-inhibited AChE. On the other hand, only HI-6 is able satisfactorily to reactivate cyclosarin-inhibited AChE.
  • In our study, we have tested six acetylcholinesterase (AChE) reactivators - pralidoxime, obidoxime, HI-6, trimedoxime, BI-6, and Hlö-7 - for reactivation of sarin and cyclosarin inhibited AChE using an in vitro reactivation test. We have used rat brain homogenate as the suitable source of enzyme. All oximes are able to reactivate sarin-inhibited AChE. On the other hand, only HI-6 is able satisfactorily to reactivate cyclosarin-inhibited AChE. (en)
  • In vitro reaktivační schopnost několika reaktivátorů AChE při inhibicích sarinem a cyklosarinem. (cs)
Title
  • In vitro reaktivační schopnost několika reaktivátorů AChE při inhibicích sarinem a cyklosarinem (cs)
  • In vitro reactivation potency of some acetylcholinesterase reactivators against sarin and cyclosarin-induced inhibitions
  • In vitro reactivation potency of some acetylcholinesterase reactivators against sarin and cyclosarin-induced inhibitions (en)
skos:prefLabel
  • In vitro reaktivační schopnost několika reaktivátorů AChE při inhibicích sarinem a cyklosarinem (cs)
  • In vitro reactivation potency of some acetylcholinesterase reactivators against sarin and cyclosarin-induced inhibitions
  • In vitro reactivation potency of some acetylcholinesterase reactivators against sarin and cyclosarin-induced inhibitions (en)
skos:notation
  • RIV/60162694:G44__/05:00001307!RIV06-MO0-G44_____
http://linked.open.../vavai/riv/strany
  • 296-300
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ONVLAJEP20031)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 524479
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/05:00001307
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • acetylcholinesterase; nerve agents; sarin; cyclosarin; reactivation; oxime (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [01E5D588933C]
http://linked.open...i/riv/nazevZdroje
  • Journal of Applied Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 25
http://linked.open...iv/tvurceVysledku
  • Cabal, Jiří
  • Kassa, Jiří
  • Kuča, Kamil
  • Jun, Daniel
  • Bartošová, Lucie
  • Kunešová, Gabriela
issn
  • 0260-437X
number of pages
http://localhost/t...ganizacniJednotka
  • G44
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