About: Signs of cyclosarin-induced neurotoxicity and its pharmacological treatment with quaternary pyridinium-oximes reactivators

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About: Signs of cyclosarin-induced neurotoxicity and its pharmacological treatment with quaternary pyridinium-oximes reactivators Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cyclosarin caused a marked statistically significant change in most of the neurobehavioral parameters (FOB) at 24 h and 7 days after exposure, compared to the saline control group. Survival was 7/10 at 24 h and 5/10 at 7 days. Oxime (BI-6, HS-6 or HI-6) + atropine treatment caused a progressing recovery of the neurobehavioral disturbances caused by cyclosarin at 24 h and 7 days after exposure. Cyclosarin caused a marked statistically significant change in most of the neurobehavioral parameters (FOB) at 24 h and 7 days after exposure, compared to the saline control group. Survival was 7/10 at 24 h and 5/10 at 7 days. Oxime (BI-6, HS-6 or HI-6) + atropine treatment caused a progressing recovery of the neurobehavioral disturbances caused by cyclosarin at 24 h and 7 days after exposure. (en) Znaky cyklosarinem způsobené neurotoxicity a jejich farmakologická léčba pomocí kvarterních pyridinium-oximových reaktivátorů. (cs)
Title	Znaky cyklosarinem způsobené neurotoxicity a jejich farmakologická léčba pomocí kvarterních pyridinium-oximových reaktivátorů (cs) Signs of cyclosarin-induced neurotoxicity and its pharmacological treatment with quaternary pyridinium-oximes reactivators Signs of cyclosarin-induced neurotoxicity and its pharmacological treatment with quaternary pyridinium-oximes reactivators (en)
skos:prefLabel	Znaky cyklosarinem způsobené neurotoxicity a jejich farmakologická léčba pomocí kvarterních pyridinium-oximových reaktivátorů (cs) Signs of cyclosarin-induced neurotoxicity and its pharmacological treatment with quaternary pyridinium-oximes reactivators Signs of cyclosarin-induced neurotoxicity and its pharmacological treatment with quaternary pyridinium-oximes reactivators (en)
skos:notation	RIV/60162694:G44__/05:00001300!RIV06-MO0-G44_____
http://linked.open.../vavai/riv/strany	32-40
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ONVLAJEP20031)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Bartošová, Lucie Kuča, Kamil Kunešová, Gabriela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	542598
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/05:00001300
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cyclosarin; Functional observational battery; Oximes; Atropine; Rats; Nerve agents; Acetylcholinesterase; Reactivators (en)
http://linked.open.../riv/klicoveSlovo	Acetylcholinesterase Nerve agents Oximes Rats Atropine Functional observational battery Reactivators Cyclosarin
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[85A88E554BD1]
http://linked.open...i/riv/nazevZdroje	Toxicology
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	New possibilities of therapy of cyclosin intoxication: Synthesis and testing of new acethylcholinesterase reactivators
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	216
http://linked.open...iv/tvurceVysledku	Kuča, Kamil Bartošová, Lucie Kunešová, Gabriela
issn	0300-483X
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	G44

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