About: Reactivation of organophosphate inhibited acetylcholinesterase activity by a,w-bis-(4-hydroxyiminomethylpyridinium) alcanes in vitro     Goto   Sponge   NotDistinct   Permalink

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  • In this article, we have followed up the relationship between the ability to reactivate acetylcholinesterase inhibited by organophosphorus compounds and the length of linking chainbetween two 4-hydroxyiminomethylpyridinium rings of acetylcholinesterase reactivators. aw-bis(4-hydroxyiminomethylpyridinium) alkanes have been used as the tested acetylcholinesterase reactivators. These oximes differ in the number of methylene groups on the connecting chain. A three or four membered linking chain seems to bethe ideal length for the satisfactory reactivation potency with the exception of reactivators of cyclosarin-inhibited acetylcholinesterase. In this case, the most efficacious acetylcholinesterase reactivator has one methylene group on the connecting chain
  • In this article, we have followed up the relationship between the ability to reactivate acetylcholinesterase inhibited by organophosphorus compounds and the length of linking chainbetween two 4-hydroxyiminomethylpyridinium rings of acetylcholinesterase reactivators. aw-bis(4-hydroxyiminomethylpyridinium) alkanes have been used as the tested acetylcholinesterase reactivators. These oximes differ in the number of methylene groups on the connecting chain. A three or four membered linking chain seems to bethe ideal length for the satisfactory reactivation potency with the exception of reactivators of cyclosarin-inhibited acetylcholinesterase. In this case, the most efficacious acetylcholinesterase reactivator has one methylene group on the connecting chain (en)
  • Reaktivace aktivity acetylcholinesterázy inhibované organofosfáty pomocí a,w-bis-(4-hydroxyiminomethylpyridinium)alkanes in vitro (cs)
Title
  • Reaktivace aktivity acetylcholinesterázy inhibované organofosfáty pomocí a,w-bis-(4-hydroxyiminomethylpyridinium)alkanes in vitro (cs)
  • Reactivation of organophosphate inhibited acetylcholinesterase activity by a,w-bis-(4-hydroxyiminomethylpyridinium) alcanes in vitro
  • Reactivation of organophosphate inhibited acetylcholinesterase activity by a,w-bis-(4-hydroxyiminomethylpyridinium) alcanes in vitro (en)
skos:prefLabel
  • Reaktivace aktivity acetylcholinesterázy inhibované organofosfáty pomocí a,w-bis-(4-hydroxyiminomethylpyridinium)alkanes in vitro (cs)
  • Reactivation of organophosphate inhibited acetylcholinesterase activity by a,w-bis-(4-hydroxyiminomethylpyridinium) alcanes in vitro
  • Reactivation of organophosphate inhibited acetylcholinesterase activity by a,w-bis-(4-hydroxyiminomethylpyridinium) alcanes in vitro (en)
skos:notation
  • RIV/60162694:G38__/03:00000903!RIV/2005/MO0/G38005/N
http://linked.open.../vavai/riv/strany
  • 207-211
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(OBVLAJEP20032), P(ON03021100001)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 624635
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G38__/03:00000903
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • acetylcholinesterase;organophosporus compounds;tabun;sarin;cyclosarin;VX (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [46DDF41B2772]
http://linked.open...i/riv/nazevZdroje
  • Journal of Applied Biomedicine
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 1
http://linked.open...iv/tvurceVysledku
  • Cabal, Jiří
  • Kuča, Kamil
  • Patočka, Jiří
issn
  • 1214-021X
number of pages
http://localhost/t...ganizacniJednotka
  • G38
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