About: A combination of pyridostigmine with anticholinergic drugs: effective pharmacological pretreatment of soman-poisoned mice     Goto   Sponge   NotDistinct   Permalink

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  • In the case of a threat of soman exposure, it seems to be very important to have sufficiently effective pretreatment because soman-induced deleterious effects are extraordinarily difficult to counteract due to the rapid aging and the existence of soman depot in the poisoned organism. Our results confirm the shortage of effectiveness of pyridostigmine to increase the resistance of soman-exposed mice in the case of treated as well as non-treated acute poisoning. On the other hand, our data show that the pretreatment mixture PANPAL is able to significantly protect soman-poisoned mice as well as increase the efficacy of antidotal pretreatment regardless of the type of oxime us
  • In the case of a threat of soman exposure, it seems to be very important to have sufficiently effective pretreatment because soman-induced deleterious effects are extraordinarily difficult to counteract due to the rapid aging and the existence of soman depot in the poisoned organism. Our results confirm the shortage of effectiveness of pyridostigmine to increase the resistance of soman-exposed mice in the case of treated as well as non-treated acute poisoning. On the other hand, our data show that the pretreatment mixture PANPAL is able to significantly protect soman-poisoned mice as well as increase the efficacy of antidotal pretreatment regardless of the type of oxime us (en)
  • Kombinace pyridostigminu s antcholinergními látkami: efektivní farmakologická profylaxe somanem otrávených myší (cs)
Title
  • A combination of pyridostigmine with anticholinergic drugs: effective pharmacological pretreatment of soman-poisoned mice
  • A combination of pyridostigmine with anticholinergic drugs: effective pharmacological pretreatment of soman-poisoned mice (en)
  • Kombinace pyridostigminu s antcholinergními látkami: efektivní farmakologická profylaxe somanem otrávených myší (cs)
skos:prefLabel
  • A combination of pyridostigmine with anticholinergic drugs: effective pharmacological pretreatment of soman-poisoned mice
  • A combination of pyridostigmine with anticholinergic drugs: effective pharmacological pretreatment of soman-poisoned mice (en)
  • Kombinace pyridostigminu s antcholinergními látkami: efektivní farmakologická profylaxe somanem otrávených myší (cs)
skos:notation
  • RIV/60162694:G38__/01:00000519!RIV/2005/MO0/G38005/N
http://linked.open.../vavai/riv/strany
  • 16-19
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MO0990200X002)
http://linked.open...iv/cisloPeriodika
  • 3
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  • 672055
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  • RIV/60162694:G38__/01:00000519
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  • Anticholinergic drugs;pyridostigmine;soman-poisoned mice (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [2970CD862B28]
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  • ASA Newsletter
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http://linked.open...v/svazekPeriodika
  • 84
http://linked.open...iv/tvurceVysledku
  • Bajgar, Jiří
  • Kassa, Jiří
  • Fusek, Josef
  • Vachek, Josef
http://linked.open...n/vavai/riv/zamer
issn
  • 1057-9419
number of pages
http://localhost/t...ganizacniJednotka
  • G38
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