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| Description
| - The expression of calcium-binding protein S100A9 was investigated in 23 matchedsets of colorectal carcinoma and normal colon mucosa using two-dimensional gelelectrophoresis. We found that, from a group of 23 patients, the level of S100A9protein, in comparison with matched normal colon mucosa, was significantlyincreased in malignant tissues of 16 patients (70%). Furthermore, an additionalprotein, identified by matrix-assisted laser desorption/ionization - massspectrometry (MALDI-MS) as S100A8, exhibited an increased expression in the samespecimens of malignant tissues as the S100A9 protein. The immunohistologicalanalysis revealed the accumulation of S100A9 positive cells, macrophages andpolymorphonuclear leukocytes along the invasive margin of colorectal carcinoma.The S100A8 protein was found to be produced in the same location. The possibleparticipation of both proteins and, especially, its heterodimeric complexcalprotectin in colorectal carcinoma regression could be taken into account.
- The expression of calcium-binding protein S100A9 was investigated in 23 matchedsets of colorectal carcinoma and normal colon mucosa using two-dimensional gelelectrophoresis. We found that, from a group of 23 patients, the level of S100A9protein, in comparison with matched normal colon mucosa, was significantlyincreased in malignant tissues of 16 patients (70%). Furthermore, an additionalprotein, identified by matrix-assisted laser desorption/ionization - massspectrometry (MALDI-MS) as S100A8, exhibited an increased expression in the samespecimens of malignant tissues as the S100A9 protein. The immunohistologicalanalysis revealed the accumulation of S100A9 positive cells, macrophages andpolymorphonuclear leukocytes along the invasive margin of colorectal carcinoma.The S100A8 protein was found to be produced in the same location. The possibleparticipation of both proteins and, especially, its heterodimeric complexcalprotectin in colorectal carcinoma regression could be taken into account. (en)
- Analýza exprese S100A9 a S100A8 proteinů v jednotlivých párech vzorků normální tkáně a nádorů tlustého střeva . S100A9 a S1008 proteiny jsou lokalizovány v okolí nádorů a také pronikají dovnitř (cs)
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| Title
| - The analyssis of S100A9 and S100A8 expression in matched sets of macroscopically normal colon mucosa and colorectal carcinoma: The S100A9 and S100A8 positive cells underlie and invade tumor mass
- The analyssis of S100A9 and S100A8 expression in matched sets of macroscopically normal colon mucosa and colorectal carcinoma: The S100A9 and S100A8 positive cells underlie and invade tumor mass (en)
- Analýza exprese S100A9 a S100A8 proteinů v jednotlivých párech vzorků normální tkáně a nádorů tlustého střeva . S100A9 a S1008 proteiny jsou lokalizovány v okolí nádorů a také pronikají dovnitř (cs)
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| skos:prefLabel
| - The analyssis of S100A9 and S100A8 expression in matched sets of macroscopically normal colon mucosa and colorectal carcinoma: The S100A9 and S100A8 positive cells underlie and invade tumor mass
- The analyssis of S100A9 and S100A8 expression in matched sets of macroscopically normal colon mucosa and colorectal carcinoma: The S100A9 and S100A8 positive cells underlie and invade tumor mass (en)
- Analýza exprese S100A9 a S100A8 proteinů v jednotlivých párech vzorků normální tkáně a nádorů tlustého střeva . S100A9 a S1008 proteiny jsou lokalizovány v okolí nádorů a také pronikají dovnitř (cs)
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| skos:notation
| - RIV/60162694:G38__/00:00000449!RIV/2005/MSM/G38005/N
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G38__/00:00000449
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - analyssis;S100A9;S100A8;colon mucosa;colorectal carcinoma;tumor mass (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/mistoVydani
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| http://linked.open...vEdiceCisloSvazku
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Bureš, Jan
- Stulík, Jiří
- Knížek, Jiří
- Macela, Aleš
- Österreicher, Jan
- Dědič, Karel
- Langr, František
- Jungblut, P. R.
- Koupilová, Kamila
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| number of pages
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| http://purl.org/ne...btex#hasPublisher
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| https://schema.org/isbn
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| http://localhost/t...ganizacniJednotka
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