About: The proportion of circulating gammadelta T cells increases after the first week of onset of tularemia and remains elevated for more than a year

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About: The proportion of circulating gammadelta T cells increases after the first week of onset of tularemia and remains elevated for more than a year Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Zastoupení cirkulujících gamma/delta T-lymfocytů roste po prvém týdnu od nástupu tularemie a zůstává zvýšené po více než rok (cs) In various human intracellular bacterial diseases, an increase of the proportion of circulating Vgamma9Vdelta2 T cells has been observed. The prevalence of the finding among infected subjects and the time course of the elevation remain to be investigated. In the present study, comprising blood samples from a large number of cases of ulceroglandular tularaemia, the percentage of Vgamma9Vdelta2 T cells within the first week of onset of disease (5.3 +/- 0.7% (mean +/- s.e.m.)) did not differ from that of control subjects (5.3 +/- 0. 8%). Thereafter, percentages increased rapidly and within the interval of 8-40 days mean levels were > 20% (P < 0.001). Of 45 individuals sampled within 3 months of onset, 42 showed a percentage of Vgamma9Vdelta2 T cells of >10%. Significantly increased levels were still recorded at 18 months (13.8 +/- 2.4%; P < 0.05) but not at 24 months (10.2 # 2.1%; P > 0.10). Thus, a consistent increase of circulating Vgamma9Vdelta2 T cells was demonstrated in tularaemia. In various human intracellular bacterial diseases, an increase of the proportion of circulating Vgamma9Vdelta2 T cells has been observed. The prevalence of the finding among infected subjects and the time course of the elevation remain to be investigated. In the present study, comprising blood samples from a large number of cases of ulceroglandular tularaemia, the percentage of Vgamma9Vdelta2 T cells within the first week of onset of disease (5.3 +/- 0.7% (mean +/- s.e.m.)) did not differ from that of control subjects (5.3 +/- 0. 8%). Thereafter, percentages increased rapidly and within the interval of 8-40 days mean levels were > 20% (P < 0.001). Of 45 individuals sampled within 3 months of onset, 42 showed a percentage of Vgamma9Vdelta2 T cells of >10%. Significantly increased levels were still recorded at 18 months (13.8 +/- 2.4%; P < 0.05) but not at 24 months (10.2 # 2.1%; P > 0.10). Thus, a consistent increase of circulating Vgamma9Vdelta2 T cells was demonstrated in tularaemia. (en)
Title	Zastoupení cirkulujících gamma/delta T-lymfocytů roste po prvém týdnu od nástupu tularemie a zůstává zvýšené po více než rok (cs) The proportion of circulating gammadelta T cells increases after the first week of onset of tularemia and remains elevated for more than a year The proportion of circulating gammadelta T cells increases after the first week of onset of tularemia and remains elevated for more than a year (en)
skos:prefLabel	Zastoupení cirkulujících gamma/delta T-lymfocytů roste po prvém týdnu od nástupu tularemie a zůstává zvýšené po více než rok (cs) The proportion of circulating gammadelta T cells increases after the first week of onset of tularemia and remains elevated for more than a year The proportion of circulating gammadelta T cells increases after the first week of onset of tularemia and remains elevated for more than a year (en)
skos:notation	RIV/60162694:G38__/00:00000363!RIV/2005/MO0/G38005/N
http://linked.open.../vavai/riv/strany	280-284
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LN00A033), Z(MO0990200X003)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Kroča, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany (nerozlišená součást)
http://linked.open...dnocenehoVysledku	723806
http://linked.open...ai/riv/idVysledku	RIV/60162694:G38__/00:00000363
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	circulating gammadelta T cells;tularemia (en)
http://linked.open.../riv/klicoveSlovo	tularemia circulating gammadelta T cells
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[D8588205DC6F]
http://linked.open...i/riv/nazevZdroje	Clinical and Experimental Immunology
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	The proteome center for the study of intracellular parasitism of microbes
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	120
http://linked.open...iv/tvurceVysledku	Kroča, Michal Sjostedt, Anders Tarnvik, Arne
http://linked.open...n/vavai/riv/zamer	Prevence v hygieně a epidemiologii
issn	0009-9104
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	G38

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