| Attributes | Values |
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| rdf:type
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| Description
| - Vliv Bcg lokusu na přirozenou rezistenci k primární infekci intracelulární bakterií Francisella tularensis LVS u myší (cs)
- The implication of the Bcg locus in the control of natural resistance toinfection with a live vaccine strain (LVS) of the intracellular pathogenFrancisella tularensis was studied. Analysis of phenotypic expression of naturalresistance and susceptibilitywas performed using mouse strains congenic at theBcg locus. Comparison of the kinetics of bacterial colonization of spleen showedthat B10.A.Bcg(r) mice were extremely susceptible during early phases of primarysublethal infection, while their congenic C57BL/10N [Bcg(s)] counterparts couldbe classified as resistant to F. tularensis LVS infection according to the2-log-lower bacterial CFU within the tissue as long as 5 days after infection.Different phenotypes of Bcg congenic mice were associated with differentialexpression of the cytokines tumor necrosis factor alpha, interleukin-10, andgamma interferon and production of reactive oxygen intermediates. These resultsstrongly suggest that the Bcg locus, which is close or identical to the Nramp1gene, controls
- The implication of the Bcg locus in the control of natural resistance toinfection with a live vaccine strain (LVS) of the intracellular pathogenFrancisella tularensis was studied. Analysis of phenotypic expression of naturalresistance and susceptibilitywas performed using mouse strains congenic at theBcg locus. Comparison of the kinetics of bacterial colonization of spleen showedthat B10.A.Bcg(r) mice were extremely susceptible during early phases of primarysublethal infection, while their congenic C57BL/10N [Bcg(s)] counterparts couldbe classified as resistant to F. tularensis LVS infection according to the2-log-lower bacterial CFU within the tissue as long as 5 days after infection.Different phenotypes of Bcg congenic mice were associated with differentialexpression of the cytokines tumor necrosis factor alpha, interleukin-10, andgamma interferon and production of reactive oxygen intermediates. These resultsstrongly suggest that the Bcg locus, which is close or identical to the Nramp1gene, controls (en)
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| Title
| - Vliv Bcg lokusu na přirozenou rezistenci k primární infekci intracelulární bakterií Francisella tularensis LVS u myší (cs)
- Influence of the Bcg locus on natural resistance to primary infection with the facultative intracellular bacterium Francisella tularensis in mice
- Influence of the Bcg locus on natural resistance to primary infection with the facultative intracellular bacterium Francisella tularensis in mice (en)
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| skos:prefLabel
| - Vliv Bcg lokusu na přirozenou rezistenci k primární infekci intracelulární bakterií Francisella tularensis LVS u myší (cs)
- Influence of the Bcg locus on natural resistance to primary infection with the facultative intracellular bacterium Francisella tularensis in mice
- Influence of the Bcg locus on natural resistance to primary infection with the facultative intracellular bacterium Francisella tularensis in mice (en)
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| skos:notation
| - RIV/60162694:G38__/00:00000360!RIV/2005/MO0/G38005/N
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GA310/99/1185), P(LN00A033), P(MO66020398130), Z(AV0Z5020903)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G38__/00:00000360
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Bcg locus;Francisella tularensis;natural resistance (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Hernychová, Lenka
- Hajdúch, Marián
- Šírová, Milada
- Kovářová, Hana
- Macela, Aleš
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
| |
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