About: The long term effects of low-level sarin inhalation exposure on cognitive functions in rats

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To study the influence of low level sarin exposure on cognitive functions, male albino Wistar rats were exposed to low concentrations of sarin for 60 minutes in the inhalation chamber. Three concentrations of sarin were chosen: clinically and laboratory asymptomatic concentration (0.8 mg/L) - LEVEL 1 clinically aymptomatic concentration with significant inhibition of erythrocyte acetylcholinesterase (1.25 mg/L) - LEVEL 2 non-convulsive symptomatic concentration (2.5 mg/L) - LEVEL 3 In addition,one group of rats was exposed to clinically asymptomatic concentration (1.25 mg/L) of sarin repeatedly (three times during one week). Testing of cognitive functions was carried out using the Y-maze evaluating learning and spatial memory. The avoidanc e behaviour of sarin-exposed rats in the Y-maze was tested several times within seven weeks following sarin inhalation exposure to look for any cognitive impairments. The results were compared to the Y-maze performance of control rats exposed to pure air To study the influence of low level sarin exposure on cognitive functions, male albino Wistar rats were exposed to low concentrations of sarin for 60 minutes in the inhalation chamber. Three concentrations of sarin were chosen: clinically and laboratory asymptomatic concentration (0.8 mg/L) - LEVEL 1 clinically aymptomatic concentration with significant inhibition of erythrocyte acetylcholinesterase (1.25 mg/L) - LEVEL 2 non-convulsive symptomatic concentration (2.5 mg/L) - LEVEL 3 In addition,one group of rats was exposed to clinically asymptomatic concentration (1.25 mg/L) of sarin repeatedly (three times during one week). Testing of cognitive functions was carried out using the Y-maze evaluating learning and spatial memory. The avoidanc e behaviour of sarin-exposed rats in the Y-maze was tested several times within seven weeks following sarin inhalation exposure to look for any cognitive impairments. The results were compared to the Y-maze performance of control rats exposed to pure air (en)
Title	The long term effects of low-level sarin inhalation exposure on cognitive functions in rats The long term effects of low-level sarin inhalation exposure on cognitive functions in rats (en)
skos:prefLabel	The long term effects of low-level sarin inhalation exposure on cognitive functions in rats The long term effects of low-level sarin inhalation exposure on cognitive functions in rats (en)
skos:notation	RIV/60162694:G16__/01:00000517!RIV/2002/MO0/G16002/N
http://linked.open.../vavai/riv/strany	CD rom
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MO0990200X002)
http://linked.open...vai/riv/dodaniDat	2002
http://linked.open...aciTvurceVysledku	Vachek, Josef Koupilová, Marie Kassa, Jiří Bajgar, Jiří
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	685508
http://linked.open...ai/riv/idVysledku	RIV/60162694:G16__/01:00000517
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Sarin; ong term effects; nhalation; cognitive functions (en)
http://linked.open.../riv/klicoveSlovo	ong term effects cognitive functions Sarin nhalation
http://linked.open...ontrolniKodProRIV	[531D974B4533]
http://linked.open...i/riv/mistoVydani	Stockholm
http://linked.open...vEdiceCisloSvazku	Neuveden
http://linked.open...i/riv/nazevZdroje	Proceedings of Seventh International Symposium on protection against chemical and biological warfare agents
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...UplatneniVysledku	2001
http://linked.open...iv/tvurceVysledku	Bajgar, Jiří Kassa, Jiří Vachek, Josef Koupilová, Marie
http://linked.open...n/vavai/riv/zamer	Ochrana proti C agens
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Commitee of Symposium
http://localhost/t...ganizacniJednotka	G44

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