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| rdf:type
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| Description
| - Kinetoplastids are flagellated protozoans, whose members include the pathogens Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, that are considered among the earliest diverging eukaryotes with a mitochondrion. This organelle has become famous because of its many unusual properties, which are unique to the order Kinetoplastida, including an extensive kinetoplast DNA network and U-insertion/deletion type RNA editing of its mitochondrial transcripts. In the last decade, considerable progress has been made in elucidating the complex machinery of RNA editing. Moreover, our understanding of the structure and replication of kinetoplast DNA has also dramatically improved. Much less is known, however, about the developmental regulation of RNA editing, its integration with other RNA maturation processes, stability of mitochondrial mRNAs, or evolution of the editing process itself.
- Kinetoplastids are flagellated protozoans, whose members include the pathogens Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, that are considered among the earliest diverging eukaryotes with a mitochondrion. This organelle has become famous because of its many unusual properties, which are unique to the order Kinetoplastida, including an extensive kinetoplast DNA network and U-insertion/deletion type RNA editing of its mitochondrial transcripts. In the last decade, considerable progress has been made in elucidating the complex machinery of RNA editing. Moreover, our understanding of the structure and replication of kinetoplast DNA has also dramatically improved. Much less is known, however, about the developmental regulation of RNA editing, its integration with other RNA maturation processes, stability of mitochondrial mRNAs, or evolution of the editing process itself. (en)
- Bičíkovci řádu Kinetoplastida zahrnují výzmanné patogeny, jakými jsou Trypanosoma brucei, Trypanosoma cruzi a Leishmania spp., kteří jsou zároveň považováni za jednu z nejčasnějších eukaryotických větví. Mají vysoce neobvyklou mitochondrii s charakteristickou kinetoplastovou DNA a editováním transkriptů inserční a deleční formou. V posledním desetiletí došlo k velkému pokroku při objasňování mechanismu a funkce editování. Rovněž se výrazně zlepšilo naše chápání struktury a replikace kinetoplastové DNA. Mnohem méně však víme o vývojové regulaci editování, jeho vzájemné integraci s ostatními procesy zrání RNA, stabilitě transkriptů a evoluci všech těchto procesů. (cs)
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| Title
| - Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates
- Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates (en)
- Nevysvětlená složitost mitochondriálního genomu a transkriptomu u kinetoplastových bičíkovců (cs)
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| skos:prefLabel
| - Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates
- Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates (en)
- Nevysvětlená složitost mitochondriálního genomu a transkriptomu u kinetoplastových bičíkovců (cs)
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| skos:notation
| - RIV/60077409:_____/05:00025930!RIV06-AV0-60077409
|
| http://linked.open.../vavai/riv/strany
| |
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(IAA5022302), Z(AV0Z60220518), Z(MSM6007665801)
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| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/60077409:_____/05:00025930
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - RNA editing; kinetoplast DNA; mRNA stability (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Lukeš, Julius
- Hashimi, Hassan
- Zíková, Alena
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| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
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