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rdf:type
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rdfs:seeAlso
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Description
| - The biosynthetic pathway leading to Xanthohumol (X) and desmethylxanthohumol (DMX) in lupulin glands is controlled by the chalcone synthase CHS_H1, prenyltransferase and Omethyltransferase 1. Despite relative simplicity of this pathway, quantitative character of inheritance of X suggests a complexity of regulatory factors controlling the biosynthesis of these metabolites of lupulin. Our recent results revealed involvement of several key transcription factors from Myb, bHLH, WDR and WRKY families in the regulation of chs_H1 and omt1 genes. We have identified lupulin specific ternary MBW complexes strongly activating chs_H1. In addition, the results show that some TFs act in binary interactions and that such complexes are quite selective for different promoters of chs-related genes. Moreover, we demonstrated the ability of some of TFs either to moderate (HlbZip1 and 2) or to inhibit (HlMyb7) transcription from chs_H1 and omt1 genes in heterologous systems.
- The biosynthetic pathway leading to Xanthohumol (X) and desmethylxanthohumol (DMX) in lupulin glands is controlled by the chalcone synthase CHS_H1, prenyltransferase and Omethyltransferase 1. Despite relative simplicity of this pathway, quantitative character of inheritance of X suggests a complexity of regulatory factors controlling the biosynthesis of these metabolites of lupulin. Our recent results revealed involvement of several key transcription factors from Myb, bHLH, WDR and WRKY families in the regulation of chs_H1 and omt1 genes. We have identified lupulin specific ternary MBW complexes strongly activating chs_H1. In addition, the results show that some TFs act in binary interactions and that such complexes are quite selective for different promoters of chs-related genes. Moreover, we demonstrated the ability of some of TFs either to moderate (HlbZip1 and 2) or to inhibit (HlMyb7) transcription from chs_H1 and omt1 genes in heterologous systems. (en)
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Title
| - Molecular Background and Networking Putatively Involved in Regulation of Lupulin Gland Metabolome – Results and Prospects
- Molecular Background and Networking Putatively Involved in Regulation of Lupulin Gland Metabolome – Results and Prospects (en)
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skos:prefLabel
| - Molecular Background and Networking Putatively Involved in Regulation of Lupulin Gland Metabolome – Results and Prospects
- Molecular Background and Networking Putatively Involved in Regulation of Lupulin Gland Metabolome – Results and Prospects (en)
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skos:notation
| - RIV/60077344:_____/13:00425866!RIV14-AV0-60077344
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - I, P(GA13-03037S), P(QH81052)
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60077344:_____/13:00425866
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - transcription factors; promoter activation; Humulus lupulus L. (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Proceedings of the International Humulus Symposium /3./
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Matoušek, Jaroslav
- Patzak, J.
- Kocábek, Tomáš
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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number of pages
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http://purl.org/ne...btex#hasPublisher
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https://schema.org/isbn
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