About: Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects     Goto   Sponge   NotDistinct   Permalink

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  • Glucagon is conventionally regarded as a hyperglycaemic hormone, which increases hepatic glucose output to the blood. Interestingly, glucagon-like peptides from the major fragment of proglucagon may also modulate response to stress in addition to their other physiological actions. These unique modes of action occur in response to stress situations and mirror the role of adipokinetic hormones (AKHs) in insects which perform a similar function. The findings on the anti-stress roles of glucagon and glucagon-like peptides in mammalian and non-mammalian vertebrates may throw light on the multiple stress responsive mechanisms which operate in a concerted manner under regulation by AKH in insects thus functioning as a stress responsive hormone.
  • Glucagon is conventionally regarded as a hyperglycaemic hormone, which increases hepatic glucose output to the blood. Interestingly, glucagon-like peptides from the major fragment of proglucagon may also modulate response to stress in addition to their other physiological actions. These unique modes of action occur in response to stress situations and mirror the role of adipokinetic hormones (AKHs) in insects which perform a similar function. The findings on the anti-stress roles of glucagon and glucagon-like peptides in mammalian and non-mammalian vertebrates may throw light on the multiple stress responsive mechanisms which operate in a concerted manner under regulation by AKH in insects thus functioning as a stress responsive hormone. (en)
Title
  • Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects
  • Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects (en)
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  • Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects
  • Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects (en)
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  • RIV/60077344:_____/13:00383049!RIV14-AV0-60077344
http://linked.open...avai/riv/aktivita
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  • I, P(GAP501/10/1215)
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  • 1
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  • 112622
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  • RIV/60077344:_____/13:00383049
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  • adipokinetic hormone; glucagon; glucagon-like peptide (en)
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  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [6316B24C7880]
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  • Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology
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  • 164
http://linked.open...iv/tvurceVysledku
  • Kodrík, Dalibor
  • Krishnan, N.
  • Bednářová, Andrea
http://linked.open...ain/vavai/riv/wos
  • 000312421400013
issn
  • 1095-6433
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.cbpa.2012.10.012
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