About: Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3. In monocentric chromosomes, the centromere is characterized by a single CenH3-containing region within a morphologically distinct primary constriction. This region usually spans up to a few Mbp composed mainly of centromere-specific satellite DNA common to all chromosomes of a given species. In holocentric chromosomes, there is no primary constriction; the centromere is composed of many CenH3 loci distributed along the entire length of a chromosome. Using correlative fluorescence light microscopy and high-resolution electron microscopy, we show that pea (Pisum sativum) chromosomes exhibit remarkably long primary constrictions that contain 3–5 explicit CenH3-containing regions, a novelty in centromere organization. The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3. In monocentric chromosomes, the centromere is characterized by a single CenH3-containing region within a morphologically distinct primary constriction. This region usually spans up to a few Mbp composed mainly of centromere-specific satellite DNA common to all chromosomes of a given species. In holocentric chromosomes, there is no primary constriction; the centromere is composed of many CenH3 loci distributed along the entire length of a chromosome. Using correlative fluorescence light microscopy and high-resolution electron microscopy, we show that pea (Pisum sativum) chromosomes exhibit remarkably long primary constrictions that contain 3–5 explicit CenH3-containing regions, a novelty in centromere organization. (en)
Title	Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains (en)
skos:prefLabel	Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains (en)
skos:notation	RIV/60077344:_____/12:00377728!RIV15-GA0-60077344
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP501/11/1843), P(GBP501/12/G090), P(LH11058), Z(AV0Z50510513)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Steinbauerová, Veronika Neumann, Pavel Macas, Jiří Novák, Petr Koblížková, Andrea Navrátilová, Alice Zemanová, Eva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	171720
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/12:00377728
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pisum sativum L.; Histone H3; plant centromers; holocentric chromosomes (en)
http://linked.open.../riv/klicoveSlovo	Pisum sativum L. Histone H3 holocentric chromosomes plant centromers
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[68CB73B60F65]
http://linked.open...i/riv/nazevZdroje	PLoS Genetics
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Evolution and Function of Complex Plant Genomes The role of repetitive DNA in plant genome architecture and function Impact of repetitive sequences on structure, evolution and function of plant centromeres
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Macas, Jiří Novák, Petr Neumann, Pavel Steinbauerová, Veronika Koblížková, Andrea Navrátilová, Alice Chocholová, Eva Schroeder-Reiter, E. Wanner, G.
http://linked.open...ain/vavai/riv/wos	000305961000039
http://linked.open...n/vavai/riv/zamer	Výzkum struktury genetické informace rostlin a jejich patogenů na molekulární úrovni, indukce a analýza cílených změn genomu a plastomu a studium fotosyntetických procesů a projevů dědičnosti v interakci s prostředím a patogeny
issn	1553-7404
number of pages	13 (xsd:int)
http://bibframe.org/vocab/doi	10.1371/journal.pgen.1002777

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