About: Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis

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About: Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Trichobilharzia regenti and T. szidati are schistosomes that infect birds. Although T. regenti/T. szidati can only complete their life cycle in specific bird hosts, their larvae -cercariae are able to penetrate, transform and then migrate as schistosomula in nonspecific hosts. Peptidases are among the key molecules produced by these schistosomes that enable parasite invasion and survival within the host. These enzymes are indispensable bio catalysts in a number of basal biological processes and host parasite interactions, e.g., tissue invasion/migration, nutrition and immune evasion. Similar biochemical and functional characteristics were observed for cathepsins B1 and B2 in bird schistosomes and also for their homologs in human schistosomes (Schistosoma mansoni, S. japonicum). Therefore, data obtained in the research of bird schistosomes can also be exploited for the control of human schistosomes such as the search for targets of novel chemotherapeutic drugs and vaccines. Trichobilharzia regenti and T. szidati are schistosomes that infect birds. Although T. regenti/T. szidati can only complete their life cycle in specific bird hosts, their larvae -cercariae are able to penetrate, transform and then migrate as schistosomula in nonspecific hosts. Peptidases are among the key molecules produced by these schistosomes that enable parasite invasion and survival within the host. These enzymes are indispensable bio catalysts in a number of basal biological processes and host parasite interactions, e.g., tissue invasion/migration, nutrition and immune evasion. Similar biochemical and functional characteristics were observed for cathepsins B1 and B2 in bird schistosomes and also for their homologs in human schistosomes (Schistosoma mansoni, S. japonicum). Therefore, data obtained in the research of bird schistosomes can also be exploited for the control of human schistosomes such as the search for targets of novel chemotherapeutic drugs and vaccines. (en)
Title	Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis (en)
skos:prefLabel	Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis (en)
skos:notation	RIV/60077344:_____/11:00364747!RIV12-AV0-60077344
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z60220518)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Dvořák, Jan
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	189300
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/11:00364747
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Trichobilharzia; trematode; Schistosoma; Fasciola; peptidase; cercarial elastase; cathepsin; hydrolysis; blood digestion; tissue migration; biochemical characterization; phylogeny; function (en)
http://linked.open.../riv/klicoveSlovo	phylogeny hydrolysis Fasciola Schistosoma Trichobilharzia biochemical characterization blood digestion cathepsin cercarial elastase function peptidase tissue migration trematode
http://linked.open...ontrolniKodProRIV	[27A1D5AD1724]
http://linked.open...i/riv/mistoVydani	BERLIN
http://linked.open...vEdiceCisloSvazku	Advances in Experimental Medicine and Biology, 712
http://linked.open...i/riv/nazevZdroje	Cysteine Proteases of Pathogenic Organisms Cysteine Proteases of Pathogenic Organisms
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...v/pocetStranKnihy	222 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Dolečková, K. Dvořák, Jan Hampl, V. Horák, P. Kašný, M. Mikeš, L. Novotný, M.
http://linked.open...n/vavai/riv/zamer	Parazitismus a parazito-hostitelské vztahy na organismální, buněčné a molekulové úrovni
number of pages	19 (xsd:int)
http://purl.org/ne...btex#hasPublisher	SPRINGER-VERLAG BERLIN, HEIDELBERGER PLATZ 3, D-14197
https://schema.org/isbn	978-1-4419-8413-5

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