About: Morphological changes in human neural cells followign tick-borne encephalitis infection

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Tick-borne encephalitis (TBE) is one of the leading and most dangerous human viral neuroinfections in Europe and north-eastern Asia. The clinical manifestations include asymptomatic infections, fevers and debilitating encephalitis that might progress into chronic disease or fatal infection. To understand TBE pathology further in host nervous systems, three human neural cell lines, neuroblastoma, medulloblastoma and glioblastoma, were infected with TBE virus (TBEV). The susceptibility and virus-mediated cytopathic effect, including ultrastructural and apoptotic changes of the cells, were examined. The neuropathological significance of the observations is discussed. Tick-borne encephalitis (TBE) is one of the leading and most dangerous human viral neuroinfections in Europe and north-eastern Asia. The clinical manifestations include asymptomatic infections, fevers and debilitating encephalitis that might progress into chronic disease or fatal infection. To understand TBE pathology further in host nervous systems, three human neural cell lines, neuroblastoma, medulloblastoma and glioblastoma, were infected with TBE virus (TBEV). The susceptibility and virus-mediated cytopathic effect, including ultrastructural and apoptotic changes of the cells, were examined. The neuropathological significance of the observations is discussed. (en)
Title	Morphological changes in human neural cells followign tick-borne encephalitis infection Morphological changes in human neural cells followign tick-borne encephalitis infection (en)
skos:prefLabel	Morphological changes in human neural cells followign tick-borne encephalitis infection Morphological changes in human neural cells followign tick-borne encephalitis infection (en)
skos:notation	RIV/60077344:_____/09:00335287!RIV10-MSM-60077344
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA524/08/1509), P(LC06009), Z(AV0Z60220518), Z(MSM6007665801)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Tesařová, Martina Kopecký, Jan Grubhoffer, Libor Růžek, Daniel Vancová, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	327474
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/09:00335287
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	tick-borne encephalitis virus; human neural cells; central nervous system (en)
http://linked.open.../riv/klicoveSlovo	central nervous system human neural cells tick-borne encephalitis virus
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[5B2B82F10B4F]
http://linked.open...i/riv/nazevZdroje	Journal of General Virology
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre for molecular ecology of vectors and pathogens Molecular pathogenesis of tick-borne encephalitis
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	90
http://linked.open...iv/tvurceVysledku	Grubhoffer, Libor Kopecký, Jan Růžek, Daniel Vancová, Marie Tesařová, Martina Ahantarig, A.
http://linked.open...ain/vavai/riv/wos	000267955900013
http://linked.open...n/vavai/riv/zamer	Parazitismus a parazito-hostitelské vztahy na organismální, buněčné a molekulové úrovni EKOLOGICKÉ, EVOLUČNÍ A EXPERIMENTÁLNĚ BIOLOGICKÉ PŘÍSTUPY KE STUDIU VZNIKU A VÝZNAMU BIODIVERZITY
issn	0022-1317
number of pages	10 (xsd:int)

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