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| rdf:type
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| Description
| - Many parasitic Apicomplexa contain an unpigmented chloroplast remnant termed apicoplast, which is a target for malaria treatment. However, no close relative of apicomplexans with a functional photosynthetic plastid has yet been known. Here we describe a newly cultured organism that has ultrastructural features typical of alveolates, is phylogenetically related to apicomplexans, and contains a photosynthetic plastid. The plastid is surrounded by four membranes, is pigmented by chlorophyll a, and uses the codon UGA to encode tryptophan in the psbA gene. This genetic feature has been found only in coccidian apicoplasts and various mitochondria. The UGA-Trp codon and phylogenies of plastid and nuclear ribosomal RNA genes indicate that the organism is the closest known photosynthetic relative to apicomplexan parasites and that its plastid shares an origin with the apicoplasts. The discovery provides a powerful model with which to study the evolution of parasitism in Apicomplexa.
- Many parasitic Apicomplexa contain an unpigmented chloroplast remnant termed apicoplast, which is a target for malaria treatment. However, no close relative of apicomplexans with a functional photosynthetic plastid has yet been known. Here we describe a newly cultured organism that has ultrastructural features typical of alveolates, is phylogenetically related to apicomplexans, and contains a photosynthetic plastid. The plastid is surrounded by four membranes, is pigmented by chlorophyll a, and uses the codon UGA to encode tryptophan in the psbA gene. This genetic feature has been found only in coccidian apicoplasts and various mitochondria. The UGA-Trp codon and phylogenies of plastid and nuclear ribosomal RNA genes indicate that the organism is the closest known photosynthetic relative to apicomplexan parasites and that its plastid shares an origin with the apicoplasts. The discovery provides a powerful model with which to study the evolution of parasitism in Apicomplexa. (en)
- Mnoho parazitických výtrusovců (Apicomplexa) obsahuje nefotosyntetický pozůstatek plastidu, nazývaný též apikoplast, který je cílem pro léčbu malárie. Nicméně, žádný blízce příbuzný výtrusovců s funkčním fotosyntetickým plastidem nebyl dosud popsán. Tato práce popisuje nově kultivovaný organismus, který obsahuje ultrastrukturní znaky alveolát, je fylogeneticky příbuzný výtrusovcům a obsahuje fotosyntetický plastid. Tento plastid je obalem čtyřmi membránami, pigmentován chlorofylem a a používá nekanonický kód UGA pro tryptofan v psbA genu. Tento genetický znak byl dosud nalezen pouze v apikoplastu kokcidií a v různých mitochondriích. Používání UGA-Trp kodonu a fylogenetická analýza na základě jaderných a plastidových genů ukazuje, že nově objevený organismus je nejbližší známý fotosyntetický příbuzný parazitů kmene Apicomplexa a jeho plastid sdílí společný původ s apikoplastem. Tento objev přináší zcela nový model pro studium evoluce parazitismu u prvoků kmene Apicomplexa. (cs)
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| Title
| - A photosynthetic alveolate closely related to apicomplexan parasites
- A photosynthetic alveolate closely related to apicomplexan parasites (en)
- Fotosyntetický alveolát blízce příbuzný parazitům kmene Apicomplexa (cs)
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| skos:prefLabel
| - A photosynthetic alveolate closely related to apicomplexan parasites
- A photosynthetic alveolate closely related to apicomplexan parasites (en)
- Fotosyntetický alveolát blízce příbuzný parazitům kmene Apicomplexa (cs)
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| skos:notation
| - RIV/60077344:_____/08:00319108!RIV09-GA0-60077344
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GA206/06/1439), S, Z(AV0Z60220518)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60077344:_____/08:00319108
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - alveolate; photosynthesis; Chromera velia; evolution; Apicomplexa (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Vancová, Marie
- Šlapeta, J.
- Oborník, Miroslav
- Chrudimský, Tomáš
- Janouškovec, Jan
- Moore, R. B.
- Bolch, Ch. J. S.
- Carter, D. A.
- Davies, N. W.
- Green, D. H.
- Heimann, K.
- Hoegh-Guldberg, O.
- Logsdon, J. M.
- Wright, S. W.
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| http://linked.open...ain/vavai/riv/wos
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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