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  • V reakci na potřebu účinně kontrolovat populace savců-škůdců a přitom se vyhnout jejich nadměrnému utrpení přišli vědci s myšlenkou virem stimulované imunokontracepce (VVIC). Dosud však k posouzení dopadů této metody používali výhradně nesexuální modely, přestože virus ovlivňuje buď pouze samce či pouze samice. V tomto článku srovnáváme predikce nesexuálních a sexuálních modelů, abychom posoudili adekvátnost použití nesexuálních modelů v tomto kontextu. Výsledky ukazují, že predikce obou typů modelů se rozcházejí a že tedy nesexuální modely obecně selhávají v predikci účinků VVIC. Analýza také ukazuje, že viry sterilizující samice jsou obecně účinnější než viry sterilizující samce, a že výběr vhodného viru by měl být více zaměřen na jeho sterilizující účinek než na jeho schopnost transmise. (cs)
  • In response to the need to efficiently control mammal pest populations while avoiding unnecessary suffering, applied and theoretical ecologists have recently focused on virus-vectored immunocontraception (VVIC). So far, modellers have only considered a non-sexual approach, which appears dubious in view of the sex-specificity of VVIC agents. In this paper, we derive and compare predictions of non-sexual and two-sex models of the spread of a VVIC agent in a host population in order to assess the adequacy of non-sexual models in this context. Our results show that predictions of non-sexual and two-sex models generally diverge and that non-sexual models often fail to predict the control impact of VVIC. Our analysis also shows that female-specific viruses generally give better results than male-specific ones, and suggests that virus choice should focus more on its sterilizing power rather than transmission efficiency.
  • In response to the need to efficiently control mammal pest populations while avoiding unnecessary suffering, applied and theoretical ecologists have recently focused on virus-vectored immunocontraception (VVIC). So far, modellers have only considered a non-sexual approach, which appears dubious in view of the sex-specificity of VVIC agents. In this paper, we derive and compare predictions of non-sexual and two-sex models of the spread of a VVIC agent in a host population in order to assess the adequacy of non-sexual models in this context. Our results show that predictions of non-sexual and two-sex models generally diverge and that non-sexual models often fail to predict the control impact of VVIC. Our analysis also shows that female-specific viruses generally give better results than male-specific ones, and suggests that virus choice should focus more on its sterilizing power rather than transmission efficiency. (en)
Title
  • Are non-sexual models appropriate for predicting the impact of virus-vectored immunocontraception?
  • Are non-sexual models appropriate for predicting the impact of virus-vectored immunocontraception? (en)
  • Jsou nesexuální modely vhodné pro predikci dopadů virem stimulované imunokontracepce? (cs)
skos:prefLabel
  • Are non-sexual models appropriate for predicting the impact of virus-vectored immunocontraception?
  • Are non-sexual models appropriate for predicting the impact of virus-vectored immunocontraception? (en)
  • Jsou nesexuální modely vhodné pro predikci dopadů virem stimulované imunokontracepce? (cs)
skos:notation
  • RIV/60077344:_____/08:00306476!RIV08-AV0-60077344
http://linked.open.../vavai/riv/strany
  • 281;290
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(IAA100070601), R, Z(AV0Z50070508)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 356993
http://linked.open...ai/riv/idVysledku
  • RIV/60077344:_____/08:00306476
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • biological control; mammal pest; population dynamics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [A72B3E8F9F06]
http://linked.open...i/riv/nazevZdroje
  • Journal of Theoretical Biology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 250
http://linked.open...iv/tvurceVysledku
  • Berec, Luděk
  • Boukal s., David
  • Courchamp, F.
  • Deredec, A.
http://linked.open...n/vavai/riv/zamer
issn
  • 0022-5193
number of pages
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