About: Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We have conducted a multifactorial genetic analysis of the Leishmania donovani complex that includes DNA sequences of protein-coding genes as well as noncoding segments, microsatellites, restriction-fragment length polymorphisms, and randomly amplified polymorphic DNAs, for a total of approximate to 18,000 characters for each of 25 geographically representative strains. Genotype is strongly correlated with geographical (continental) origin, but not with current taxonomy or clinical outcome. We propose a new taxonomy, in which Leishmania infantum and L. donovani are the only recognized species of the L. donovani complex, and we present an evolutionary hypothesis for the origin and dispersal of the species. We have conducted a multifactorial genetic analysis of the Leishmania donovani complex that includes DNA sequences of protein-coding genes as well as noncoding segments, microsatellites, restriction-fragment length polymorphisms, and randomly amplified polymorphic DNAs, for a total of approximate to 18,000 characters for each of 25 geographically representative strains. Genotype is strongly correlated with geographical (continental) origin, but not with current taxonomy or clinical outcome. We propose a new taxonomy, in which Leishmania infantum and L. donovani are the only recognized species of the L. donovani complex, and we present an evolutionary hypothesis for the origin and dispersal of the species. (en) Provedli jsme multifaktoriální genetickou analýzu komplexu Leishmania donovani, která zahrnuje sekvenování protein kódujících genů a nekódujících úseků, mikrosatelity, RFLP a RAPD data. Celkem bylo hodnoceno 18000 znaků pro každý z 25 kmenů. Genotyp silně koreluje s geografickým původem, ovšem nikoliv se současnou taxonomií. Navrhli jsme novou taxonomii komplexu zahrnující pouze druhy L. infantum a L. donovani a zároveň jsme navrhli hypotézu vzniku tohoto komplexu a rozšíření těchto druhů. (cs)
Title	Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy Evoluční a geografická historie komplexu Leishmania donovani a revize současné taxonomie (cs) Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy (en)
skos:prefLabel	Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy Evoluční a geografická historie komplexu Leishmania donovani a revize současné taxonomie (cs) Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy (en)
skos:notation	RIV/60077344:_____/07:00087514!RIV08-AV0-60077344
http://linked.open.../vavai/riv/strany	9375;9380
http://linked.open...avai/riv/aktivita	P R Z
http://linked.open...avai/riv/aktivity	P(2B06129), P(LC07032), R, Z(AV0Z60220518)
http://linked.open...iv/cisloPeriodika	22
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Jirků, Milan Lukeš, Julius Oborník, Miroslav Horák, Aleš Zemanová, Eva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	420885
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/07:00087514
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	leishmaniasis; parasitic protozoa; phylogeny; population genetics (en)
http://linked.open.../riv/klicoveSlovo	parasitic protozoa phylogeny population genetics leishmaniasis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[149441B3AD24]
http://linked.open...i/riv/nazevZdroje	Proceedings of the National Academy of Sciences of the United States of America
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	16 (xsd:int)
http://linked.open...vavai/riv/projekt	Model organisms as a key to the understanding of functions of disease-related human genes Center for Functional Genetics
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	104
http://linked.open...iv/tvurceVysledku	Horák, Aleš Jirků, Milan Lukeš, Julius Zemanová, Eva Oborník, Miroslav Ayala, F. J. Mauricio, I. L. Miles, M. A. Schönian, G. Dedet, J.-P. Pratlong, F. Dujardin, J.-C. Haralambous, C. Kuhls, K. QuispeTintaya, K. W. Soteriadou, K.
http://linked.open...n/vavai/riv/zamer	Parazitismus a parazito-hostitelské vztahy na organismální, buněčné a molekulové úrovni
issn	0027-8424
number of pages	6 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software