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| Description
| - We describe DNA sequence polymorphisms at six loci (Acp26Aa, Acp26Ab, Acp29AB, Idgf1, Idgf3 and Ddc), all on the second chromosome of Drosophila melanogaster. Previous studies considering these loci separately showed that some of them were affected by natural selection. However, demographic processes can produce footprints similar to natural selection. Simultaneous consideration of several genes may help to discern between selective and demography/admixture scenarios. Since different evolutionary forces shaped the variation of the studied genes, we examined if their physical linkage could have affected the observed pattern. While Fisher's conservative test is not significant, Lewontin's sign test pointed to linkage disequilibrium both within and between loci levels, though, none of the loci exhibits haplotype structure. Coupled with other results, the possibility of demography being the exclusive explanation for the observed variability is ruled out.
- We describe DNA sequence polymorphisms at six loci (Acp26Aa, Acp26Ab, Acp29AB, Idgf1, Idgf3 and Ddc), all on the second chromosome of Drosophila melanogaster. Previous studies considering these loci separately showed that some of them were affected by natural selection. However, demographic processes can produce footprints similar to natural selection. Simultaneous consideration of several genes may help to discern between selective and demography/admixture scenarios. Since different evolutionary forces shaped the variation of the studied genes, we examined if their physical linkage could have affected the observed pattern. While Fisher's conservative test is not significant, Lewontin's sign test pointed to linkage disequilibrium both within and between loci levels, though, none of the loci exhibits haplotype structure. Coupled with other results, the possibility of demography being the exclusive explanation for the observed variability is ruled out. (en)
- Práce se zabývá polymorfismem DNA sekvencí u šesti genů (Acp26Aa, Acp26Ab, Acp29AB, Idgf1, Idgf3 a Ddc), které se nacházejí na druhém chromozomu Drosophila melanogaster. Dřívější studie jednotlivých genů prokázaly, že některé z nich byly ovlivněny přírodním výběrem. Nicméně, demografické procesy mohou rovněž zanechat stopy podobné selekci. Pro rozlišení mezi selekcí a demografií je nutno zvážit několik genů současně. Vzhledem k tomu, že uvedené geny vykazovaly rozdílné modely evoluce, jsme zjišťovali, do jaké míry mohla tuto skutečnost ovlivnit jejich fyzická vazba. Zatímco Fisherův konzervativní test byl neprůkazný, Lewontinův znaménkový test prokázal vazebnou nerovnováhu jak mezi geny, tak i uvnitř genů samotných. Žádný z lokusů však nevykazoval haplotypovou strukturu. Na základě těchto a dalších výsledků lze vyloučit, že by demografie byla výlučným procesem ovlivňujícím pozorovanou variabilitu. (cs)
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| Title
| - Differences in the pattern of evolution in six physically linked genes of Drosophila melanogaster
- Rozdíly v modelu evoluce u šesti fyzicky vázaných genů u Drosophila melanogaster (cs)
- Differences in the pattern of evolution in six physically linked genes of Drosophila melanogaster (en)
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| skos:prefLabel
| - Differences in the pattern of evolution in six physically linked genes of Drosophila melanogaster
- Rozdíly v modelu evoluce u šesti fyzicky vázaných genů u Drosophila melanogaster (cs)
- Differences in the pattern of evolution in six physically linked genes of Drosophila melanogaster (en)
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| skos:notation
| - RIV/60077344:_____/06:00041590!RIV07-AV0-60077344
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GA204/03/1383), P(LC06077), Z(AV0Z50070508), Z(MSM6007665801)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60077344:_____/06:00041590
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - DNA polymorphism; demography; linkage disequilibrium (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Berec, Luděk
- Žurovcová, Martina
- Tatarenkov, A.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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