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| rdf:type
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| Description
| - Cytochrom P450 je významným biochemickým markerem pro hodnocení kontaminace povrchových vod širokou škálou průmyslových polutantů. Cytochrom P450 je monooxydázový enzymatický komplex přítomný prakticky ve všech živých organismech a podílející se na biotransformaci látek endogenního původu i xenobiotik. Jeho indukci vyvolává aktivita některých cizorodých látek a může přetrvávat až několik měsíců. Jeho koncentrace je stanovována spektrofluorometricky ve vzorcích jater ryb. Rostoucí aktivita cytochromu P450 je propojena s rostoucí aktivitou dalších enzymů. V rybách vzrůstá aktivita ethoxyresorufin-O-deethylasy, která je také využívána pro hodnocení zatížení vodních ekosystémů. V průběhu hodnocení kontaminace řeky Labe byly za účelem stanovení biochemických markerů (cytochrom P450, ethoxyresorufin-O-deethylasa) odebrány vzorky na 10 různě zatížených lokalitách. Nejvyšší znečištění bylo prokázáno v lokalitách Zelčín a Valy, které se nacházely pod velkými chemickými továrnami. (cs)
- Cytochrome P450 is a significant biochemical marker of Labe river contamination for assessment of surface water contamination by a large scale of industrial pollutants. Cytochrome P450 is a mono-oxygenase enzymatic complex occuring practically in all live organisms, which is responsible for biotransformation of endogenous substances and xenobiotics. The activity of some pollutants causes its induction that may last even over period of several months. Its concentration is determined spectrophorometrically from fish liver samples. The increased cytochrome P450 activity is linked to increased activation of further enzymes. In fish there occurs an increase of ethoxyresorufin-O-deethylase, which is also utilized for an assessment of burdens of water ecosystems. During monitoring programme of river Labe pollution the samples from 10 differently polluted locations were collected to determine their concentration of the biochemical markers i.e. cytochrome P450 and ethoxyresorufin-O-deethylase. The greatest po
- Cytochrome P450 is a significant biochemical marker of Labe river contamination for assessment of surface water contamination by a large scale of industrial pollutants. Cytochrome P450 is a mono-oxygenase enzymatic complex occuring practically in all live organisms, which is responsible for biotransformation of endogenous substances and xenobiotics. The activity of some pollutants causes its induction that may last even over period of several months. Its concentration is determined spectrophorometrically from fish liver samples. The increased cytochrome P450 activity is linked to increased activation of further enzymes. In fish there occurs an increase of ethoxyresorufin-O-deethylase, which is also utilized for an assessment of burdens of water ecosystems. During monitoring programme of river Labe pollution the samples from 10 differently polluted locations were collected to determine their concentration of the biochemical markers i.e. cytochrome P450 and ethoxyresorufin-O-deethylase. The greatest po (en)
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| Title
| - Indukce cytochromu P450 v rybách - biochemický marker kontaminace řeky Labe (cs)
- Cytochrome P450 induction in fish as a biochemical marker of Labe river contamination
- Cytochrome P450 induction in fish as a biochemical marker of Labe river contamination (en)
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| skos:prefLabel
| - Indukce cytochromu P450 v rybách - biochemický marker kontaminace řeky Labe (cs)
- Cytochrome P450 induction in fish as a biochemical marker of Labe river contamination
- Cytochrome P450 induction in fish as a biochemical marker of Labe river contamination (en)
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| skos:notation
| - RIV/60076658:12610/04:00005827!RIV/2005/MSM/126105/N
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60076658:12610/04:00005827
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - cytochrom P450;ryba;ethoxyresorufin-O-deethylasa;biochemický marker (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Toxicology and Applied Pharmacology
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Randák, Tomáš
- Svobodová, Zdeňka
- Krijt, J.
- Široká, Z.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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