About: Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost, Oncorhynchus mykiss: a comparative study of in vivo and in vitro

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About: Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost, Oncorhynchus mykiss: a comparative study of in vivo and in vitro Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Toxic effects of environmental concentrations (50, 100, and 200 mýg/L) of waterborne chromium (VI) were evaluated in rainbow trout by comparison of in vitro and in vivo assays. Multiple biomarkers were measured. Superoxide dismutase (SOD) and glutathione reductase (GR) activities were significantly induced (1.54-fold and 1.37-fold, respectively) in fish brain in vivo. Oxidative stress was apparent in vitro as significantly higher levels of oxidative indices, with the highest induction of TBARS and CP found in brain at 200 mýg/L Cr(VI) (2.41-fold and 1.95-fold, respectively), and SOD and GR activities and reduced glutathione in brain were significantly inhibited (65%, 44%, and 36%, respectively). In vitro Na+-K+-ATPase activity in gill was also significantly inhibited at concentrations of 100 and 200 mýg/L (69% and 45%, respectively). Short-term exposure to environmental concentrations of Cr(VI) does not therefore evoke marked effects in fish in vivo. Toxic effects of environmental concentrations (50, 100, and 200 mýg/L) of waterborne chromium (VI) were evaluated in rainbow trout by comparison of in vitro and in vivo assays. Multiple biomarkers were measured. Superoxide dismutase (SOD) and glutathione reductase (GR) activities were significantly induced (1.54-fold and 1.37-fold, respectively) in fish brain in vivo. Oxidative stress was apparent in vitro as significantly higher levels of oxidative indices, with the highest induction of TBARS and CP found in brain at 200 mýg/L Cr(VI) (2.41-fold and 1.95-fold, respectively), and SOD and GR activities and reduced glutathione in brain were significantly inhibited (65%, 44%, and 36%, respectively). In vitro Na+-K+-ATPase activity in gill was also significantly inhibited at concentrations of 100 and 200 mýg/L (69% and 45%, respectively). Short-term exposure to environmental concentrations of Cr(VI) does not therefore evoke marked effects in fish in vivo. (en)
Title	Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost, Oncorhynchus mykiss: a comparative study of in vivo and in vitro Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost, Oncorhynchus mykiss: a comparative study of in vivo and in vitro (en)
skos:prefLabel	Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost, Oncorhynchus mykiss: a comparative study of in vivo and in vitro Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost, Oncorhynchus mykiss: a comparative study of in vivo and in vitro (en)
skos:notation	RIV/60076658:12520/11:43880512!RIV12-MZP-12520___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(ED2.1.00/01.0024), P(GAP503/11/1130), P(SP/2E7/229/07), S
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Randák, Tomáš Li, Ping Li, Zhihua
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Jihočeská univerzita v Českých Budějovicích / Fakulta rybářství a ochrany vod
http://linked.open...dnocenehoVysledku	198247
http://linked.open...ai/riv/idVysledku	RIV/60076658:12520/11:43880512
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	In vivo/in vitro; Fish; Environmental related concentrations; Chromium (VI) (en)
http://linked.open.../riv/klicoveSlovo	Chromium (VI) Environmental related concentrations In vivo/in vitro Fish
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[CA6D6B4B4337]
http://linked.open...i/riv/nazevZdroje	Comparative Biochemistry and Physiology C - Toxicology and Pharmacology
http://linked.open...in/vavai/riv/obor	GL
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Effect of environmental levels of selected pharmaceuticals on rainbow trout (Oncorhynchus mykiss) and fish cell culture models South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses Anthropogenic pressures on the status of soils, water resources and water ecosystems in the Czech part of the international basin of the Elbe River
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	153
http://linked.open...iv/tvurceVysledku	Li, Ping Li, Zhihua Randák, Tomáš
http://linked.open...ain/vavai/riv/wos	000289383700005
issn	1532-0456
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.cbpc.2011.01.005
http://localhost/t...ganizacniJednotka	12520

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