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Description
| - The effect of human chorionic gonadotropin (hCG) stimulation on the activities of ethoxyresorufin O-deethylase (EROD), methoxyresorufin O-demethylase (MROD) and pentoxyresorufin O-depentylase (PROD) was studied in intact male pigs of purebred Landrace and Duroc breeds. We found that EROD activity was suppressed by hCG-stimulation in Landrace (p = 0.004), but not Duroc pigs (p > 0.05). Generally, EROD activity was higher in Duroc pigs compared with Landrace (p = 0.017). Methoxyresorufin O-demethylase and PROD activities did not differ between groups (p > 0.05). To further characterize EROD, MROD and PROD, enzyme kinetic studies were performed. Vmax values for EROD and MROD in both breeds were lower after hCG stimuation (p < 0.001 Landrace; p < 0.05 Duroc). Additionally, Vmax values for EROD significantly differed, being higher in Duroc pigs (p < 0.05). We concluded that both hCG stimulation and breed differences may be important in the regulativ of EROD and MROD activities.
- The effect of human chorionic gonadotropin (hCG) stimulation on the activities of ethoxyresorufin O-deethylase (EROD), methoxyresorufin O-demethylase (MROD) and pentoxyresorufin O-depentylase (PROD) was studied in intact male pigs of purebred Landrace and Duroc breeds. We found that EROD activity was suppressed by hCG-stimulation in Landrace (p = 0.004), but not Duroc pigs (p > 0.05). Generally, EROD activity was higher in Duroc pigs compared with Landrace (p = 0.017). Methoxyresorufin O-demethylase and PROD activities did not differ between groups (p > 0.05). To further characterize EROD, MROD and PROD, enzyme kinetic studies were performed. Vmax values for EROD and MROD in both breeds were lower after hCG stimuation (p < 0.001 Landrace; p < 0.05 Duroc). Additionally, Vmax values for EROD significantly differed, being higher in Duroc pigs (p < 0.05). We concluded that both hCG stimulation and breed differences may be important in the regulativ of EROD and MROD activities. (en)
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Title
| - Hepatic Ethoxy-, Methoxy- and Pentoxyresorufin O-Dealkylase Activities in Landrace and Duroc Pigs Stimulated with hCG
- Hepatic Ethoxy-, Methoxy- and Pentoxyresorufin O-Dealkylase Activities in Landrace and Duroc Pigs Stimulated with hCG (en)
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skos:prefLabel
| - Hepatic Ethoxy-, Methoxy- and Pentoxyresorufin O-Dealkylase Activities in Landrace and Duroc Pigs Stimulated with hCG
- Hepatic Ethoxy-, Methoxy- and Pentoxyresorufin O-Dealkylase Activities in Landrace and Duroc Pigs Stimulated with hCG (en)
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skos:notation
| - RIV/60076658:12520/10:00011451!RIV11-MSM-12520___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60076658:12520/10:00011451
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - CYP; EROD; MROD; PROD; HPLC; porcine (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Reproduction in Domestic Animals
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Žlábek, Vladimír
- Zamaratskaia, G.
- Andresen, O.
- Ropstad, E.
- Tajet, H.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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