About: Evaluating the function of calcium antagonist on the Cd-induced stress in sperm of Russian sturgeon, Acipenser gueldenstaedtii     Goto   Sponge   NotDistinct   Permalink

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Description
  • In the current study, the sperm of Russian sturgeon (Acipenser gueldenstaedtii) was used to evaluate the roles of Verapamil (VRP), a calcium channel blocker, against cadmium (Cd)-induced stress. Sturgeon sperm were exposed for 2 h at 50 mu g/L VRP, 5.0 mu g/L Cd, the mixture of 50 mu g/L VRP + 5.0 mu g/L Cd, 50 mu g/L Cd and the mixture of 50 mu g/L VRP + 50 mu g/L Cd. After exposure, the sperm motility parameters (motility and velocity), oxidative stress levels (lipid peroxidation [LPO] and carbonyl protein [CP]) and antioxidant enzyme activities (superoxide dismutase [SOD], glutathione reductase [GR], glutathione peroxidase [GPx]) were measured in sturgeon sperm. Compared to the control, Cd-induced stress was apparent as reflected by depressed motility parameters, induced oxidative stress and inhibited antioxidant enzyme activities at both Cd concentrations. In the presence of VRP, Cd-induced stress was reduced in sturgeon sperm, especially all the measured parameters in the sperm exposed at 5.0 mu
  • In the current study, the sperm of Russian sturgeon (Acipenser gueldenstaedtii) was used to evaluate the roles of Verapamil (VRP), a calcium channel blocker, against cadmium (Cd)-induced stress. Sturgeon sperm were exposed for 2 h at 50 mu g/L VRP, 5.0 mu g/L Cd, the mixture of 50 mu g/L VRP + 5.0 mu g/L Cd, 50 mu g/L Cd and the mixture of 50 mu g/L VRP + 50 mu g/L Cd. After exposure, the sperm motility parameters (motility and velocity), oxidative stress levels (lipid peroxidation [LPO] and carbonyl protein [CP]) and antioxidant enzyme activities (superoxide dismutase [SOD], glutathione reductase [GR], glutathione peroxidase [GPx]) were measured in sturgeon sperm. Compared to the control, Cd-induced stress was apparent as reflected by depressed motility parameters, induced oxidative stress and inhibited antioxidant enzyme activities at both Cd concentrations. In the presence of VRP, Cd-induced stress was reduced in sturgeon sperm, especially all the measured parameters in the sperm exposed at 5.0 mu (en)
Title
  • Evaluating the function of calcium antagonist on the Cd-induced stress in sperm of Russian sturgeon, Acipenser gueldenstaedtii
  • Evaluating the function of calcium antagonist on the Cd-induced stress in sperm of Russian sturgeon, Acipenser gueldenstaedtii (en)
skos:prefLabel
  • Evaluating the function of calcium antagonist on the Cd-induced stress in sperm of Russian sturgeon, Acipenser gueldenstaedtii
  • Evaluating the function of calcium antagonist on the Cd-induced stress in sperm of Russian sturgeon, Acipenser gueldenstaedtii (en)
skos:notation
  • RIV/60076658:12520/10:00011447!RIV11-MZP-12520___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED2.1.00/01.0024), P(SP/2E7/229/07), S, Z(MSM6007665809)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 257778
http://linked.open...ai/riv/idVysledku
  • RIV/60076658:12520/10:00011447
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Verapamil; Sturgeon sperm; Motility; Velocity; Antioxidant response; Protective role (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [33353157A34D]
http://linked.open...i/riv/nazevZdroje
  • Aquatic Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 100
http://linked.open...iv/tvurceVysledku
  • Li, Ping
  • Li, Zhihua
  • Randák, Tomáš
  • Rodina, Marek
http://linked.open...ain/vavai/riv/wos
  • 000284787200009
http://linked.open...n/vavai/riv/zamer
issn
  • 0166-445X
number of pages
http://localhost/t...ganizacniJednotka
  • 12520
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