About: Modulation of glutathione-related antioxidant defense system of fish chronically treated by the fungicide propiconazole

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About: Modulation of glutathione-related antioxidant defense system of fish chronically treated by the fungicide propiconazole Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Recently, residual fungicides are generally recognized as relevant sources of aquatic environmental pollutants. However, the toxicological effects of these contaminants have not been adequately researched. In this study, the chronic effect of PCZ, a triazole-containing fungicide commonly present in aquatic environment, on GSH-related antioxidant system and oxidative stress indices of rainbow trout (Oncorhynchus mykiss) were investigated. Fish were exposed at sub-lethal concentrations of PCZ (0.2, 50 and 500 mu g/L) for 7, 20 and 30 days. GSH levels and GSH-related enzyme activities, including GPx, GR and GST, were quantified in three tissues liver, gill and muscle. The levels of LPO and CP were also measured as makers of oxidative damage. In addition, the correlations of the measured parameters in various tissues were evaluated by using PCA. The results of this study indicate that chronic exposure of PCZ has resulted in different responses in various tissues and the gill was the most sensitive tissue; Recently, residual fungicides are generally recognized as relevant sources of aquatic environmental pollutants. However, the toxicological effects of these contaminants have not been adequately researched. In this study, the chronic effect of PCZ, a triazole-containing fungicide commonly present in aquatic environment, on GSH-related antioxidant system and oxidative stress indices of rainbow trout (Oncorhynchus mykiss) were investigated. Fish were exposed at sub-lethal concentrations of PCZ (0.2, 50 and 500 mu g/L) for 7, 20 and 30 days. GSH levels and GSH-related enzyme activities, including GPx, GR and GST, were quantified in three tissues liver, gill and muscle. The levels of LPO and CP were also measured as makers of oxidative damage. In addition, the correlations of the measured parameters in various tissues were evaluated by using PCA. The results of this study indicate that chronic exposure of PCZ has resulted in different responses in various tissues and the gill was the most sensitive tissue; (en)
Title	Modulation of glutathione-related antioxidant defense system of fish chronically treated by the fungicide propiconazole Modulation of glutathione-related antioxidant defense system of fish chronically treated by the fungicide propiconazole (en)
skos:prefLabel	Modulation of glutathione-related antioxidant defense system of fish chronically treated by the fungicide propiconazole Modulation of glutathione-related antioxidant defense system of fish chronically treated by the fungicide propiconazole (en)
skos:notation	RIV/60076658:12520/10:00011413!RIV11-MZP-12520___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(SP/2E7/229/07), Z(MSM6007665809)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Randák, Tomáš Grabic, Roman Žlábek, Vladimír Li, Ping Li, Zhihua
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Jihočeská univerzita v Českých Budějovicích / Fakulta rybářství a ochrany vod
http://linked.open...dnocenehoVysledku	272334
http://linked.open...ai/riv/idVysledku	RIV/60076658:12520/10:00011413
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Fish; Oxidative stress; Residual fungicide; Glutathione (en)
http://linked.open.../riv/klicoveSlovo	Oxidative stress Fish Glutathione Residual fungicide
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[979703E4B303]
http://linked.open...i/riv/nazevZdroje	Comparative Biochemistry and Physiology C - Toxicology and Pharmacology
http://linked.open...in/vavai/riv/obor	GL
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Anthropogenic pressures on the status of soils, water resources and water ecosystems in the Czech part of the international basin of the Elbe River
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	152
http://linked.open...iv/tvurceVysledku	Grabic, Roman Li, Ping Li, Zhihua Randák, Tomáš Žlábek, Vladimír
http://linked.open...ain/vavai/riv/wos	000280902400020
http://linked.open...n/vavai/riv/zamer	Biologické, enviromentální a chovatelské aspekty v rybářství
issn	1532-0456
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	12520

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