About: Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine

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About: Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The chronic toxic effects of carbamazepine (CBZ) on rainbow trout were investigated. Fish were exposed at sublethal concentrations of CBZ (1.0 μg.l-1, 0.2 mg l-1 and 2.0 mg.l-1) for 42 days. Compared with the control, there was a significant lower (P < 0.05) condition factor in fish exposed at the highest concentration of CBZ (2.0 mg.l-1), but the hepatosomatic indices in all groups were not significant changes. At lower CBZ concentration (1.0 μg.l-1, 0.2 mg.l-1), the antioxidant enzyme activities were induced slightly, except catalase, while at the highest concentration (2.0 mg.l-1) oxidative stress was apparent as reflected by the significant higher lipid peroxidation and protein carbonyls in the fish muscle, associated with a significant inhibition of antioxidant enzymes activities. Moreover, energy metabolic parameters (RNA-DNA ratio, Na+-K+-ATPase) were significantly inhibited in muscle of the fish exposed at the highest concentration (2.0 mg.l-1), compared with the control. The chronic toxic effects of carbamazepine (CBZ) on rainbow trout were investigated. Fish were exposed at sublethal concentrations of CBZ (1.0 μg.l-1, 0.2 mg l-1 and 2.0 mg.l-1) for 42 days. Compared with the control, there was a significant lower (P < 0.05) condition factor in fish exposed at the highest concentration of CBZ (2.0 mg.l-1), but the hepatosomatic indices in all groups were not significant changes. At lower CBZ concentration (1.0 μg.l-1, 0.2 mg.l-1), the antioxidant enzyme activities were induced slightly, except catalase, while at the highest concentration (2.0 mg.l-1) oxidative stress was apparent as reflected by the significant higher lipid peroxidation and protein carbonyls in the fish muscle, associated with a significant inhibition of antioxidant enzymes activities. Moreover, energy metabolic parameters (RNA-DNA ratio, Na+-K+-ATPase) were significantly inhibited in muscle of the fish exposed at the highest concentration (2.0 mg.l-1), compared with the control. (en)
Title	Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine (en)
skos:prefLabel	Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine Physiological condition status and Muscle based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine (en)
skos:notation	RIV/60076658:12520/10:00011403!RIV11-MZP-12520___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(SP/2E7/229/07), Z(MSM6007665809)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Velíšek, Josef Máchová, Jana Randák, Tomáš Grabic, Roman Žlábek, Vladimír Li, Zhihua
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Jihočeská univerzita v Českých Budějovicích / Fakulta rybářství a ochrany vod
http://linked.open...dnocenehoVysledku	278934
http://linked.open...ai/riv/idVysledku	RIV/60076658:12520/10:00011403
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Fish; residual pharmaceutical; oxidative stress; condition factor; hepatosomatic index; RNA-DNA ratio; Na+-K+-ATPase (en)
http://linked.open.../riv/klicoveSlovo	condition factor Fish oxidative stress hepatosomatic index RNA-DNA ratio residual pharmaceutical Na+-K+-ATPase
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[EBB4B1A76E20]
http://linked.open...i/riv/nazevZdroje	Journal of Applied Toxicology
http://linked.open...in/vavai/riv/obor	GL
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Anthropogenic pressures on the status of soils, water resources and water ecosystems in the Czech part of the international basin of the Elbe River
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	30
http://linked.open...iv/tvurceVysledku	Grabic, Roman Li, Zhihua Máchová, Jana Randák, Tomáš Velíšek, Josef Žlábek, Vladimír
http://linked.open...ain/vavai/riv/wos	000277524000002
http://linked.open...n/vavai/riv/zamer	Biologické, enviromentální a chovatelské aspekty v rybářství
issn	0260-437X
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	12520

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