About: Age related susceptibility of pigs to Cryptosporidium scrofarum infection

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S0304401714000855
Description	Piglets from 4 to 8 weeks of age originated from a Cryptosporidium-free research breed were orally inoculated with 1 x 106 infectious oocysts of Cryptosporidium scrofarum. The number of shed oocysts per gram of faeces served to describe the infection intensity and prepatent period. In addition, faecal samples collected daily and tissue samples of the small and large intestine collected at 30 days post-inoculation were examined for the C. scrofarum small subunit ribosomal RNA gene using PCR. The piglets inoculated at 4-weeks of age remained uninfected, whereas 5-week-old and older animals were fully susceptible with a prepatent period ranging from 4 to 8 days. Susceptible pigs shed oocysts intermittently, and shedding intensity, reaching a mean maximum of 6000 oocysts per gram, did not differ significantly among infected animals. This study demonstrates that pigs become susceptible to C. scrofarum infection as late as 5-weeks of age. The mechanisms of age related susceptibility remain unknown. Piglets from 4 to 8 weeks of age originated from a Cryptosporidium-free research breed were orally inoculated with 1 x 106 infectious oocysts of Cryptosporidium scrofarum. The number of shed oocysts per gram of faeces served to describe the infection intensity and prepatent period. In addition, faecal samples collected daily and tissue samples of the small and large intestine collected at 30 days post-inoculation were examined for the C. scrofarum small subunit ribosomal RNA gene using PCR. The piglets inoculated at 4-weeks of age remained uninfected, whereas 5-week-old and older animals were fully susceptible with a prepatent period ranging from 4 to 8 days. Susceptible pigs shed oocysts intermittently, and shedding intensity, reaching a mean maximum of 6000 oocysts per gram, did not differ significantly among infected animals. This study demonstrates that pigs become susceptible to C. scrofarum infection as late as 5-weeks of age. The mechanisms of age related susceptibility remain unknown. (en)
Title	Age related susceptibility of pigs to Cryptosporidium scrofarum infection Age related susceptibility of pigs to Cryptosporidium scrofarum infection (en)
skos:prefLabel	Age related susceptibility of pigs to Cryptosporidium scrofarum infection Age related susceptibility of pigs to Cryptosporidium scrofarum infection (en)
skos:notation	RIV/60076658:12510/14:43887661!RIV15-MSM-12510___
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(LH11061), S
http://linked.open...iv/cisloPeriodika	3-4
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Rost, Michael
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Jihočeská univerzita v Českých Budějovicích / Ekonomická fakulta
http://linked.open...dnocenehoVysledku	1829
http://linked.open...ai/riv/idVysledku	RIV/60076658:12510/14:43887661
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cryptosporidium scrofarum, Molecular analyses, Transmission studies, Susceptibility, Infection, Pigs (en)
http://linked.open.../riv/klicoveSlovo	Cryptosporidium scrofarum Molecular analyses Transmission studies Infection Pigs Susceptibility
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[DC469A86FFD9]
http://linked.open...i/riv/nazevZdroje	Veterinary Parasitology
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Diversity, biology and phylogeny of Cryptosporidium spp. parasiting in rodents
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	202
http://linked.open...iv/tvurceVysledku	Kváč, Martin Květoňová, Dana Rost, Michael Sak, Bohumil Samková, Eva Němejc, Karel Kotková, Michaela McEvoy, John Wágnerová, Pavla Kestřánová, Michaela
http://linked.open...ain/vavai/riv/wos	000336870600035
issn	0304-4017
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.vetpar.2014.02.012
http://localhost/t...ganizacniJednotka	12510

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