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  • OBJECTIVES: The objective of the study was to assess the metabolic risk of excessive dietary iodine intake in ewes and neonatal lambs. DESIGN: Pregnant Sumava ewes received an experimental diet containing 3.1 mg iodine per kg of dietary dry matter in Group A (control, n=13, 6 ewes and 7 lambs) and 5.1 mg iodine per kg of dietary dry matter in Group B (experimental, n=12, 6 ewes, 6 lambs) for eight months. Iodine was administered to ewes as calcium iodate. TSH in blood serum; TT3, TT4, fT(3), and fT(4) in blood plasma were examined in both groups of ewes and lambs to assess the risks of iodine intake above the permitted limit, as it applies to thyroid gland activity. RESULTS: Group B ewes showed a significant increase in TSH and TT4 only on day 1 after parturition. The highest values of TT4, TT3, and fT(3) in lambs were recorded on day 1 after birth. The lowest values of fT(3) and fT(4) in lambs were measured on day 60 after birth with no differences observed between the groups. In lambs of Group B the lower concentration of TSH until day 3 after birth was followed by a significant increase from day 10 after birth. CONCLUSION: Our results indicate a risk of postnatal hypothyroidism among lambs from pregnant and lactating ewes having a high iodine intake.
  • OBJECTIVES: The objective of the study was to assess the metabolic risk of excessive dietary iodine intake in ewes and neonatal lambs. DESIGN: Pregnant Sumava ewes received an experimental diet containing 3.1 mg iodine per kg of dietary dry matter in Group A (control, n=13, 6 ewes and 7 lambs) and 5.1 mg iodine per kg of dietary dry matter in Group B (experimental, n=12, 6 ewes, 6 lambs) for eight months. Iodine was administered to ewes as calcium iodate. TSH in blood serum; TT3, TT4, fT(3), and fT(4) in blood plasma were examined in both groups of ewes and lambs to assess the risks of iodine intake above the permitted limit, as it applies to thyroid gland activity. RESULTS: Group B ewes showed a significant increase in TSH and TT4 only on day 1 after parturition. The highest values of TT4, TT3, and fT(3) in lambs were recorded on day 1 after birth. The lowest values of fT(3) and fT(4) in lambs were measured on day 60 after birth with no differences observed between the groups. In lambs of Group B the lower concentration of TSH until day 3 after birth was followed by a significant increase from day 10 after birth. CONCLUSION: Our results indicate a risk of postnatal hypothyroidism among lambs from pregnant and lactating ewes having a high iodine intake. (en)
Title
  • The impact of high iodine intake on thyroid function in ewes and lambs
  • The impact of high iodine intake on thyroid function in ewes and lambs (en)
skos:prefLabel
  • The impact of high iodine intake on thyroid function in ewes and lambs
  • The impact of high iodine intake on thyroid function in ewes and lambs (en)
skos:notation
  • RIV/60076658:12220/12:43883887!RIV13-MSM-12220___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(QH81105), S
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 140625
http://linked.open...ai/riv/idVysledku
  • RIV/60076658:12220/12:43883887
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • fT4; fT3; TT4; TT3; TSH; calcium iodate (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • SE - Švédské království
http://linked.open...ontrolniKodProRIV
  • [14D207E50416]
http://linked.open...i/riv/nazevZdroje
  • Neuroendocrinology Letters
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 33
http://linked.open...iv/tvurceVysledku
  • Konečný, Roman
  • Kroupová, Vlasta
  • Peksa, Zdeněk
  • Svoboda, Martin
  • Trávníček, Jan
  • Baňoch, Tomáš
  • Dušová, Hana
http://linked.open...ain/vavai/riv/wos
  • 000311470400009
issn
  • 0172-780X
number of pages
http://localhost/t...ganizacniJednotka
  • 12220
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