About: Biomedically relevant chemical constituents of Valeriana officinalis

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Valerian is used against sleeping disorders, restlessness and anxiety. Valerian seems only to work when taken over longer periods (several weeks). Some studies have demonstrated that valerian extracts interact with the GABA and benzodiazepine receptors. Valerian is also used traditionally to treat gastrointestinal pain and spastic colitis. Long term safety studies are missing. Valerian contains over 150 chemical constituents and many of them are physiologically active, mainly pyridine alkaloids, some organic acids and terpenes, especially so called valepotriates, esterified iridoid-monoterpenes. As valepotriates may be potential mutagens, valerian should only be used after consultation with a physician. Valerian medication is sometimes recommended as first line when benefit-risk relation requires so. Valerian is often indicated as transition medication during discontinuation processes involving bromazepam, clonazepam and diazepam, among others. Valerian is used against sleeping disorders, restlessness and anxiety. Valerian seems only to work when taken over longer periods (several weeks). Some studies have demonstrated that valerian extracts interact with the GABA and benzodiazepine receptors. Valerian is also used traditionally to treat gastrointestinal pain and spastic colitis. Long term safety studies are missing. Valerian contains over 150 chemical constituents and many of them are physiologically active, mainly pyridine alkaloids, some organic acids and terpenes, especially so called valepotriates, esterified iridoid-monoterpenes. As valepotriates may be potential mutagens, valerian should only be used after consultation with a physician. Valerian medication is sometimes recommended as first line when benefit-risk relation requires so. Valerian is often indicated as transition medication during discontinuation processes involving bromazepam, clonazepam and diazepam, among others. (en)
Title	Biomedically relevant chemical constituents of Valeriana officinalis Biomedically relevant chemical constituents of Valeriana officinalis (en)
skos:prefLabel	Biomedically relevant chemical constituents of Valeriana officinalis Biomedically relevant chemical constituents of Valeriana officinalis (en)
skos:notation	RIV/60076658:12110/10:00012128!RIV11-MSM-12110___
http://linked.open...avai/riv/aktivita	P V
http://linked.open...avai/riv/aktivity	P(QH81160), V
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Patočka, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Jihočeská univerzita v Českých Budějovicích / Zdravotně sociální fakulta
http://linked.open...dnocenehoVysledku	248948
http://linked.open...ai/riv/idVysledku	RIV/60076658:12110/10:00012128
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Valeriana officinalis; valerian; chemical constituents; alkaloids; terpenes - valepotriates (en)
http://linked.open.../riv/klicoveSlovo	alkaloids terpenes Valeriana officinalis chemical constituents valerian
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[728CF950BD70]
http://linked.open...i/riv/nazevZdroje	Journal of Applied Biomedicine
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Economic Effectiveness of Forest Tree Breeding
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Patočka, Jiří Jakl, Jiří
http://linked.open...ain/vavai/riv/wos	000274244600002
issn	1214-021X
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	12110

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