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Description
  • No alternative model for human peripheral blood cells still has been found. With respect to our previous studies on insect immunotoxicological reactions we compared the morphology of human circulating blood cells and insect haemocytes using standard haematological methods. We documented that insect prohaemocytes, granulocytes and plasmatocytes have morphology which is similar to human mature lymphocytes, neutrophil granulocytes and monocytes. It offers to start studies carried on haemocytes to be evaluated as a prospective inexpensive model for toxicological praescreening.
  • No alternative model for human peripheral blood cells still has been found. With respect to our previous studies on insect immunotoxicological reactions we compared the morphology of human circulating blood cells and insect haemocytes using standard haematological methods. We documented that insect prohaemocytes, granulocytes and plasmatocytes have morphology which is similar to human mature lymphocytes, neutrophil granulocytes and monocytes. It offers to start studies carried on haemocytes to be evaluated as a prospective inexpensive model for toxicological praescreening. (en)
  • Přehledný článek diskutující podobnost hemocytů a cirkulujících krvinek v rozsahu základních hematologických metod při vývoji biomodelů pro toxikologický preskríning. (cs)
Title
  • Does preclinical testing on insects help to predict human myelotoxic potentials?
  • Pomáhá preklinické testování na hmyzu predikci lidského myelotoxického potenciálu? (cs)
  • Does preclinical testing on insects help to predict human myelotoxic potentials? (en)
skos:prefLabel
  • Does preclinical testing on insects help to predict human myelotoxic potentials?
  • Pomáhá preklinické testování na hmyzu predikci lidského myelotoxického potenciálu? (cs)
  • Does preclinical testing on insects help to predict human myelotoxic potentials? (en)
skos:notation
  • RIV/60076658:12110/08:00009099!RIV09-MSM-12110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • SI
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http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 364119
http://linked.open...ai/riv/idVysledku
  • RIV/60076658:12110/08:00009099
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • alternative models; predictive toxicology; insect haemocytes; myelotoxicity; cytotoxicity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • JP - Japonsko
http://linked.open...ontrolniKodProRIV
  • [5E1278FE62FD]
http://linked.open...i/riv/nazevZdroje
  • AATEX
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 14
http://linked.open...iv/tvurceVysledku
  • Berger, Josef
issn
  • 1344-0411
number of pages
http://localhost/t...ganizacniJednotka
  • 12110
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