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  • This chapter considers living tissues (consisting of individual cells and the tissue matrix) from the perspective of physics. It is a review of several current approaches that are clearly physical. Beginning with thermodynamics, we examine the free-energy dependence of microscopic parameters for living tissues, and we continue with special mechanical properties of living cells and the important role of prestress in the cellular skeleton. We mention the tensegrity theory and briefly review the approach in which a cell is regarded as a soft glassy material. We then discuss the problems of description and experimental identification of properties in living tissues and use an example to outline a purely mechanical explanation for the way that smooth muscle cells efficiently control the mechanical behavior of the entire tissue. The concluding discussion summarizes the role of physical models for cell mechanics in researching the structural principles governing living matter.
  • This chapter considers living tissues (consisting of individual cells and the tissue matrix) from the perspective of physics. It is a review of several current approaches that are clearly physical. Beginning with thermodynamics, we examine the free-energy dependence of microscopic parameters for living tissues, and we continue with special mechanical properties of living cells and the important role of prestress in the cellular skeleton. We mention the tensegrity theory and briefly review the approach in which a cell is regarded as a soft glassy material. We then discuss the problems of description and experimental identification of properties in living tissues and use an example to outline a purely mechanical explanation for the way that smooth muscle cells efficiently control the mechanical behavior of the entire tissue. The concluding discussion summarizes the role of physical models for cell mechanics in researching the structural principles governing living matter. (en)
Title
  • Mechanical Properties of Living Cells and Tissues Related to Thermodynamics, Experiments and Quantitative Morphology - A Review
  • Mechanical Properties of Living Cells and Tissues Related to Thermodynamics, Experiments and Quantitative Morphology - A Review (en)
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  • Mechanical Properties of Living Cells and Tissues Related to Thermodynamics, Experiments and Quantitative Morphology - A Review
  • Mechanical Properties of Living Cells and Tissues Related to Thermodynamics, Experiments and Quantitative Morphology - A Review (en)
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  • RIV/49777513:23640/11:43898305!RIV12-GA0-23640___
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  • P(GA106/09/0734), Z(MSM4977751303)
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  • 211248
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  • RIV/49777513:23640/11:43898305
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  • experiment; biomechanics; microscopy; cytoskeleton; living cell; thermodynamics; physics (en)
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  • [BC69116C152C]
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  • Rijeka, Croatia
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  • Neuveden
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  • Theoretical Biomechanics
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  • Holeček, Miroslav
  • Kochová, Petra
  • Tonar, Zbyněk
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number of pages
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  • InTech
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  • 978-953-307-851-9
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  • 23640
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