About: Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.scopus.com/authid/detail.url?authorId=54950669200
Description	This article describes the design of equipment for the production of small-diameter fiber tubular bodies, which can be used as carrier of tissue cells, so called scaffold. It is also described the production and creation of a simulation model describing the behaviour of the tubular body under internal pressure. For this purpose electrospinning device has been created which allows obtaining the parallel fiber orientation, which is required for effective penetration of cell and mechanical properties of artifical flood vessel. Prepared scaffolds were subjected to mechanical tsting for a determination of a suitable material model.Subsequently, the FEM model of the scaffold loaded with an internal overpressure, which corresponds to normal blood pressure (120/80 mmHg) was established. The results allow assessing the behaviour of the scaffold during cell cultivation and their subsequent proliferation in fibrous structure, because a stimulation of cell proliferation is achieved by a flowing of a nutrient solution in the scaffold under changeable pressure. Based on obtained results an optimization of scaffolds was recommended. This article describes the design of equipment for the production of small-diameter fiber tubular bodies, which can be used as carrier of tissue cells, so called scaffold. It is also described the production and creation of a simulation model describing the behaviour of the tubular body under internal pressure. For this purpose electrospinning device has been created which allows obtaining the parallel fiber orientation, which is required for effective penetration of cell and mechanical properties of artifical flood vessel. Prepared scaffolds were subjected to mechanical tsting for a determination of a suitable material model.Subsequently, the FEM model of the scaffold loaded with an internal overpressure, which corresponds to normal blood pressure (120/80 mmHg) was established. The results allow assessing the behaviour of the scaffold during cell cultivation and their subsequent proliferation in fibrous structure, because a stimulation of cell proliferation is achieved by a flowing of a nutrient solution in the scaffold under changeable pressure. Based on obtained results an optimization of scaffolds was recommended. (en)
Title	Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel (en)
skos:prefLabel	Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel (en)
skos:notation	RIV/46747885:24620/14:#0000576!RIV15-MSM-24620___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(EE2.3.30.0024), P(EE2.3.30.0065), P(LO1201)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Petrů, Michal
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Technická univerzita v Liberci / Ústav pro nanomateriály, pokročilé technologie a inovace
http://linked.open...dnocenehoVysledku	15788
http://linked.open...ai/riv/idVysledku	RIV/46747885:24620/14:#0000576
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Artificial blood vessel; Electrospinning; FEM model (en)
http://linked.open.../riv/klicoveSlovo	FEM model Electrospinning Artificial blood vessel
http://linked.open...ontrolniKodProRIV	[F92723674C31]
http://linked.open...v/mistoKonaniAkce	Mariánské Lázně
http://linked.open...i/riv/mistoVydani	Plzeň
http://linked.open...i/riv/nazevZdroje	Experimental Stress Analysis 2014
http://linked.open...in/vavai/riv/obor	JQ
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	DEVELOPMENT OF THE INSTITUTE FOR NANOMATERIALS, ADVANCED TECHNOLOGIES AND INNOVATION Support of the creation of excellent research and development teams at the Technical University of Liberec Development of research teams of R & D projects at the Technical University of Liberec
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Novák, Ondřej Petrů, Michal Lepšík, Petr Vosáhlo, Josef
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2014-01-01 (xsd:date)
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Výzkumný a zkušební ústav Plzeň s.r.o
https://schema.org/isbn	978-80-261-0377-6
http://localhost/t...ganizacniJednotka	24620

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