About: In vitro antiplatelet activity of flavonoids from Leuzea carthamoides     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Byla určena protisrážlivá aktivita etanolového extraktu Leuzea carthamoides. (cs)
  • Plants and their secondary metabolites, including flavonoids, exhibit a wide range of biological effects. Consequently, natural substances are receiving an increased attention in medicinal research. Owing to these facts, in vitro antiplatelet activity of ethanol summary extract and four flavonoids from Leuzea carthamoides was determined in human platelet-rich plasma. Arachidonic acid, adenosine diphosphate, collagen, and thrombin were used as agonists of platelet aggregation. The summary extract showed a significant inhibition of the aggregation induced by and ADP. Of the tested flavonoids, eriodictyol and patuletin influenced COL and AA-induced aggregation. Their IC50 values are presented. Flavonoid glycosides eriodictyol-7-glucopyranoside and 6-hydroxykaempferol-7-O-(6-O-acetyl-Dsmall cap-glucopyranoside) were found to be weak antiplatelet agents. These results confirmed the fact that glucosylation decreases the antiplatelet activity. Quantitative composition of tested flavonoids in L. carthamoides
  • Plants and their secondary metabolites, including flavonoids, exhibit a wide range of biological effects. Consequently, natural substances are receiving an increased attention in medicinal research. Owing to these facts, in vitro antiplatelet activity of ethanol summary extract and four flavonoids from Leuzea carthamoides was determined in human platelet-rich plasma. Arachidonic acid, adenosine diphosphate, collagen, and thrombin were used as agonists of platelet aggregation. The summary extract showed a significant inhibition of the aggregation induced by and ADP. Of the tested flavonoids, eriodictyol and patuletin influenced COL and AA-induced aggregation. Their IC50 values are presented. Flavonoid glycosides eriodictyol-7-glucopyranoside and 6-hydroxykaempferol-7-O-(6-O-acetyl-Dsmall cap-glucopyranoside) were found to be weak antiplatelet agents. These results confirmed the fact that glucosylation decreases the antiplatelet activity. Quantitative composition of tested flavonoids in L. carthamoides (en)
Title
  • In vitro antiplatelet activity of flavonoids from Leuzea carthamoides
  • In vitro antiplatelet activity of flavonoids from Leuzea carthamoides (en)
  • In vitro protisrážlivá aktivita flavonoidů Leuzea carthamoides (cs)
skos:prefLabel
  • In vitro antiplatelet activity of flavonoids from Leuzea carthamoides
  • In vitro antiplatelet activity of flavonoids from Leuzea carthamoides (en)
  • In vitro protisrážlivá aktivita flavonoidů Leuzea carthamoides (cs)
skos:notation
  • RIV/44555601:13440/08:00004241!RIV09-MSM-13440___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 371776
http://linked.open...ai/riv/idVysledku
  • RIV/44555601:13440/08:00004241
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Antiplatelet activity; Flavonoids; Leuzea carthamoides; Aggregation; Plants; Quantity. (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [DD33E13FA30E]
http://linked.open...i/riv/nazevZdroje
  • Drug & Chemical Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 31
http://linked.open...iv/tvurceVysledku
  • Kuča, Kamil
  • Opletal, L.
  • Kolečkář, V.
  • Červenka, F.
  • Řeháková, Z.
  • Jůn, D.
  • Kubiková, K.
  • Brojerová, E.
  • Hronek, M.
  • Opletalová, V.
issn
  • 0148-0545
number of pages
http://localhost/t...ganizacniJednotka
  • 13440
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software