About: The fate of feedborne mycotoxins T-2 and HT-2 toxins in dairy cows

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About: The fate of feedborne mycotoxins T-2 and HT-2 toxins in dairy cows - a review Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Mycotoxins comprise a group of chemically diverse compounds originating from secondary metabolism of filamentous fungi, moulds. T-2 and HT-2 toxins are type A trichothecene mycotoxins, which are closely-related epoxy sesquiterpenoids produced primarily by Fusarium poae, F. sporotrichioides, F. langsethiae and other Fusarium spp. T-2 and HT-2 toxins contaminate mainly grains such as oat, barley, wheat and maize as well as in their by-products. HT-2 toxin is a major metabolite of T-2 toxin and they often occur together in infected cereals. The current results suggest that in general HT-2 toxin represents approximately 2/3 of the sum of T-2 toxin and HT-2 toxin. T-2 toxin is animal body rapidly metabolised by at least five biotransformation pathways including hydrolysis, hydroxylation, de-epoxidation, glucuronidation and acetylation, resulting in a large number of different metabolites. T-2 toxin and metabolites are rapidly distributed to several tissues and rapidly excreted without any accumulation. Thus any significant human exposure to these toxins from consumption of animal products is unlikely. Mycotoxins comprise a group of chemically diverse compounds originating from secondary metabolism of filamentous fungi, moulds. T-2 and HT-2 toxins are type A trichothecene mycotoxins, which are closely-related epoxy sesquiterpenoids produced primarily by Fusarium poae, F. sporotrichioides, F. langsethiae and other Fusarium spp. T-2 and HT-2 toxins contaminate mainly grains such as oat, barley, wheat and maize as well as in their by-products. HT-2 toxin is a major metabolite of T-2 toxin and they often occur together in infected cereals. The current results suggest that in general HT-2 toxin represents approximately 2/3 of the sum of T-2 toxin and HT-2 toxin. T-2 toxin is animal body rapidly metabolised by at least five biotransformation pathways including hydrolysis, hydroxylation, de-epoxidation, glucuronidation and acetylation, resulting in a large number of different metabolites. T-2 toxin and metabolites are rapidly distributed to several tissues and rapidly excreted without any accumulation. Thus any significant human exposure to these toxins from consumption of animal products is unlikely. (en)
Title	The fate of feedborne mycotoxins T-2 and HT-2 toxins in dairy cows - a review The fate of feedborne mycotoxins T-2 and HT-2 toxins in dairy cows - a review (en)
skos:prefLabel	The fate of feedborne mycotoxins T-2 and HT-2 toxins in dairy cows - a review The fate of feedborne mycotoxins T-2 and HT-2 toxins in dairy cows - a review (en)
skos:notation	RIV/26788462:_____/13:#0000660!RIV14-MZE-26788462
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(QI111B044)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Křížová, Ludmila Pavlok, Stanislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Agrovýzkum Rapotín s.r.o.
http://linked.open...dnocenehoVysledku	74739
http://linked.open...ai/riv/idVysledku	RIV/26788462:_____/13:#0000660
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	T-2 toxin; HT-2 toxin; dairy cow; rumen; absorption; excretion; milk (en)
http://linked.open.../riv/klicoveSlovo	dairy cow rumen HT-2 toxin excretion absorption milk T-2 toxin
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[348F3FFB3E0F]
http://linked.open...i/riv/nazevZdroje	Výzkum v chovu skotu
http://linked.open...in/vavai/riv/obor	GH
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Comprehensive strategy for decreasing a negative impact of Fusarium spp. toxicogenic fungi infection in cereals and their derivated products.
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	55
http://linked.open...iv/tvurceVysledku	Křížová, Ludmila Pavlok, Stanislav
issn	0139-7265
number of pages	12 (xsd:int)

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