About: Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients

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About: Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The results of our pilot study demonstrate the potential use of free DNA in the peripheral blood not only to investigate the presence of EGFR mutations and KRAS gene but also for the examination metylation status of genes important for the biological behavior of non-small cell carcinoma. EGFR mutations and KRAS were used in this study as a marker of the presence of tumor DNA in peripheral blood. The results of our pilot study demonstrate the potential use of free DNA in the peripheral blood not only to investigate the presence of EGFR mutations and KRAS gene but also for the examination metylation status of genes important for the biological behavior of non-small cell carcinoma. EGFR mutations and KRAS were used in this study as a marker of the presence of tumor DNA in peripheral blood. (en)
Title	Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients (en)
skos:prefLabel	Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients (en)
skos:notation	RIV/26475821:_____/12:#0000115!RIV12-MZ0-26475821
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NS9718)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Minárik, Marek Kopečková, Marta Benešová, Lucie Belšánová, Barbora
http://linked.open.../riv/druhVysledku	A(V) - Audiovizuální tvorba se vzdáleným přístupem
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Genomac International, s.r.o.
http://linked.open...dnocenehoVysledku	157028
http://linked.open...ai/riv/idVysledku	RIV/26475821:_____/12:#0000115
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	tumor cell-free DNA; NSCLC; genetic testing; methylation analysis (en)
http://linked.open.../riv/klicoveSlovo	NSCLC methylation analysis tumor cell-free DNA genetic testing
http://linked.open...i/riv/kodPristupu	L
http://linked.open...ontrolniKodProRIV	[ADFB470AD352]
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	New possibilities for application of molecular-diagnostic methods for early detection and proper therapy selection of progressing Non-Small Cell Lung Cancer based on detection and monitoring of hypermethylation of specific genes
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Belšánová, Barbora Benšová, Lucie Kopečková, Marta Minárik, Marek

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