About: Three-dimensional sonography of the posterior fossa in fetuses with open spina bifida at 11-13 weeks' gestation     Goto   Sponge   NotDistinct   Permalink

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  • OBJECTIVES: To investigate the posterior fossa of normal fetuses and fetuses with open spina bifida in stored three-dimensional (3D) volumes and to describe signs that might allow early detection of this defect.METHODS: A prospective study of 3D volumes of the fetal brain obtained from 10 normal fetuses and three fetuses with open spina bifida was undertaken. Measurements of the anteroposterior diameters of the cisterna magna and fourth ventricle were taken in the tilted axial view. In the mid-sagittal plane the brainstem (BS) diameter and the brainstem-occipital bone (BSOB) distance were measured. The BS/BSOB ratio was calculated. All measurements were expressed as Z-scores. Structural analysis of the differences in the posterior fossa between normal fetuses and fetuses with open spina bifida was undertaken.RESULTS: In normal fetuses all measurements were within 2.5 Z-scores. In three fetuses with open spina bifida the BS Z-scores were 2.7, 2.8 and 2.8; the BSOB scores were - 3.4, - 2.8 and - 2.9; the cisterna magna scores were - 5.6, - 3.7 and - 4.2; and the BS/BSOB ratio scores were 4.1, 9.7 and 8.9. In normal fetuses the cisterna magna was posterior to the fourth ventricle and extended along its entire length. In fetuses with open spina bifida the cisterna magna was partially or completely obliterated.CONCLUSIONS: Assessment of the cranial posterior fossa is feasible at 11-13 weeks' gestation. There are distinct signs in fetuses with open spina bifida which can be evaluated by ultrasonography.
  • OBJECTIVES: To investigate the posterior fossa of normal fetuses and fetuses with open spina bifida in stored three-dimensional (3D) volumes and to describe signs that might allow early detection of this defect.METHODS: A prospective study of 3D volumes of the fetal brain obtained from 10 normal fetuses and three fetuses with open spina bifida was undertaken. Measurements of the anteroposterior diameters of the cisterna magna and fourth ventricle were taken in the tilted axial view. In the mid-sagittal plane the brainstem (BS) diameter and the brainstem-occipital bone (BSOB) distance were measured. The BS/BSOB ratio was calculated. All measurements were expressed as Z-scores. Structural analysis of the differences in the posterior fossa between normal fetuses and fetuses with open spina bifida was undertaken.RESULTS: In normal fetuses all measurements were within 2.5 Z-scores. In three fetuses with open spina bifida the BS Z-scores were 2.7, 2.8 and 2.8; the BSOB scores were - 3.4, - 2.8 and - 2.9; the cisterna magna scores were - 5.6, - 3.7 and - 4.2; and the BS/BSOB ratio scores were 4.1, 9.7 and 8.9. In normal fetuses the cisterna magna was posterior to the fourth ventricle and extended along its entire length. In fetuses with open spina bifida the cisterna magna was partially or completely obliterated.CONCLUSIONS: Assessment of the cranial posterior fossa is feasible at 11-13 weeks' gestation. There are distinct signs in fetuses with open spina bifida which can be evaluated by ultrasonography. (en)
Title
  • Three-dimensional sonography of the posterior fossa in fetuses with open spina bifida at 11-13 weeks' gestation
  • Three-dimensional sonography of the posterior fossa in fetuses with open spina bifida at 11-13 weeks' gestation (en)
skos:prefLabel
  • Three-dimensional sonography of the posterior fossa in fetuses with open spina bifida at 11-13 weeks' gestation
  • Three-dimensional sonography of the posterior fossa in fetuses with open spina bifida at 11-13 weeks' gestation (en)
skos:notation
  • RIV/00843989:_____/11:00102122!RIV12-MZ0-00843989
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 235302
http://linked.open...ai/riv/idVysledku
  • RIV/00843989:_____/11:00102122
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • first trimester; posterior fossa; prenatal ultrasonography; spina bifida (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [13E382423905]
http://linked.open...i/riv/nazevZdroje
  • Ultrasound in obstetrics & gynecology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 38
http://linked.open...iv/tvurceVysledku
  • Lachmann, R.
  • Nicolaides, K. H.
  • Pětroš, Michal
  • Scheier, M.
http://linked.open...ain/vavai/riv/wos
  • 000298257600004
issn
  • 0960-7692
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/uog.9067
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