About: Oral rivaroxaban for symptomatic venous thromboembolism     Goto   Sponge   NotDistinct   Permalink

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Description
  • Rivaroxaban, an oral factor Xa inhibitor, may provide a simple, fixed-dose regimen for treating acute deep-vein thrombosis (DVT) and for continued treatment, without the need for laboratory monitoring. We conducted an open-label, randomized, event-driven, noninferiority study that compared oral rivaroxaban alone (15 mg twice daily for 3 weeks, followed by 20 mg once daily) with subcutaneous enoxaparin followed by a vitamin K antagonist (either warfarin or acenocoumarol) for 3, 6, or 12 months in patients with acute, symptomatic DVT. In parallel, we carried out a double-blind, randomized, event-driven superiority study that compared rivaroxaban alone (20 mg once daily) with placebo for an additional 6 or 12 months in patients who had completed 6 to 12 months offor an additional 6 or 12 months in patients who had completed 6 to 12 months of
  • Rivaroxaban, an oral factor Xa inhibitor, may provide a simple, fixed-dose regimen for treating acute deep-vein thrombosis (DVT) and for continued treatment, without the need for laboratory monitoring. We conducted an open-label, randomized, event-driven, noninferiority study that compared oral rivaroxaban alone (15 mg twice daily for 3 weeks, followed by 20 mg once daily) with subcutaneous enoxaparin followed by a vitamin K antagonist (either warfarin or acenocoumarol) for 3, 6, or 12 months in patients with acute, symptomatic DVT. In parallel, we carried out a double-blind, randomized, event-driven superiority study that compared rivaroxaban alone (20 mg once daily) with placebo for an additional 6 or 12 months in patients who had completed 6 to 12 months offor an additional 6 or 12 months in patients who had completed 6 to 12 months of (en)
Title
  • Oral rivaroxaban for symptomatic venous thromboembolism
  • Oral rivaroxaban for symptomatic venous thromboembolism (en)
skos:prefLabel
  • Oral rivaroxaban for symptomatic venous thromboembolism
  • Oral rivaroxaban for symptomatic venous thromboembolism (en)
skos:notation
  • RIV/00843989:_____/10:00101810!RIV12-MZ0-00843989
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N
http://linked.open...iv/cisloPeriodika
  • no.26
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 277456
http://linked.open...ai/riv/idVysledku
  • RIV/00843989:_____/10:00101810
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • factor-XA inhibitor; deep-vein thrombosis; therapy; prevention (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [854B5DA02DC9]
http://linked.open...i/riv/nazevZdroje
  • New England Journal of Medicine
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 363
http://linked.open...iv/tvurceVysledku
  • Matoška, Petr
  • Bauersachs, R.
http://linked.open...ain/vavai/riv/wos
  • 000285555600005
issn
  • 0028-4793
number of pages
http://bibframe.org/vocab/doi
  • 10.1056/NEJMoa1007903
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