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  • Transcranial sonography (TCS) allows high resolution imaging of deep brain structures, provided sufficient imaging conditions and adequate qualification of the investigator. Since TCS can display changes of midbrain structures and basal ganglia that are not or only heavily detected with other neuroimaging methods, TCS has yielded new insights into the pathogenesis also of non-motor features of PD. Abnormal increased echogenicity ('hyperechogenicity') of substantia nigra is not only a characteristic finding in PD, but is also related to increased risk of depression in PD patients (relative risk [RR], 1.9). Reduced echogenicity ('hypoechogenicity') of midbrain raphe indicated increased risk of depression (RR, 2.0) and urinary incontinence (RR, 4.7) in PD patients. Caudate nucleus hyperechogenicity was associated with drug-induced psychosis (RR, 2.4), and frontal-horn dilatation >20mm with dementia (RR, 3.6). TCS findings support the hypothesis of a pathogenetic link between depression an
  • Transcranial sonography (TCS) allows high resolution imaging of deep brain structures, provided sufficient imaging conditions and adequate qualification of the investigator. Since TCS can display changes of midbrain structures and basal ganglia that are not or only heavily detected with other neuroimaging methods, TCS has yielded new insights into the pathogenesis also of non-motor features of PD. Abnormal increased echogenicity ('hyperechogenicity') of substantia nigra is not only a characteristic finding in PD, but is also related to increased risk of depression in PD patients (relative risk [RR], 1.9). Reduced echogenicity ('hypoechogenicity') of midbrain raphe indicated increased risk of depression (RR, 2.0) and urinary incontinence (RR, 4.7) in PD patients. Caudate nucleus hyperechogenicity was associated with drug-induced psychosis (RR, 2.4), and frontal-horn dilatation >20mm with dementia (RR, 3.6). TCS findings support the hypothesis of a pathogenetic link between depression an (en)
Title
  • Transcranial sonography findings related to non-motor features of Parkinson´s disease
  • Transcranial sonography findings related to non-motor features of Parkinson´s disease (en)
skos:prefLabel
  • Transcranial sonography findings related to non-motor features of Parkinson´s disease
  • Transcranial sonography findings related to non-motor features of Parkinson´s disease (en)
skos:notation
  • RIV/00843989:_____/10:00100918!RIV11-MZ0-00843989
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  • 1-2
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  • 293270
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  • RIV/00843989:_____/10:00100918
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  • Parkinson´s disease; depression; dementia; urinary urge incontinence; psychosis; transcranial sonography; caudate nucleus; raphe nuclei (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [3AED7B6A1860]
http://linked.open...i/riv/nazevZdroje
  • Journal of the neurological sciences
http://linked.open...in/vavai/riv/obor
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 289
http://linked.open...iv/tvurceVysledku
  • Školoudík, David
  • Berg, D.
  • Walter, U.
http://linked.open...ain/vavai/riv/wos
  • 000274925700024
issn
  • 0022-510X
number of pages
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