About: Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus

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About: Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Therapy of posthemorrhagic hydrocephalus (PHH) by using ventriculo-peritoneal drainage bears considerable rate of complications and remains a challenge in premature newborns. The role of endoscopic third ventriculostomy (ETV) in these patients is unclear, through obstruction is proved in some patients with PHH.TGF β 1 release into the CSF in time of primary bleeding is suggested as one of possible pathophysiologic reasons of PHH formation. Relation between TGF β1 levels and ETV success rate has not been reported yet. The aim of our study is to detect group of patients, according to the levels of TGF β1, who have MRI proved obstruction hydrocefalus without participation of hyporesorption – so that we can expect success of ETV. MethodsWe followed 29 premature newborns with PHH during 2005-2007, all of them treated by Ommaya reservoir implantation and repeated taps with TGF β1 levels examination. In case of persisting hydrocephalus MRI was performed. In 16 patients with proved Therapy of posthemorrhagic hydrocephalus (PHH) by using ventriculo-peritoneal drainage bears considerable rate of complications and remains a challenge in premature newborns. The role of endoscopic third ventriculostomy (ETV) in these patients is unclear, through obstruction is proved in some patients with PHH.TGF β 1 release into the CSF in time of primary bleeding is suggested as one of possible pathophysiologic reasons of PHH formation. Relation between TGF β1 levels and ETV success rate has not been reported yet. The aim of our study is to detect group of patients, according to the levels of TGF β1, who have MRI proved obstruction hydrocefalus without participation of hyporesorption – so that we can expect success of ETV. MethodsWe followed 29 premature newborns with PHH during 2005-2007, all of them treated by Ommaya reservoir implantation and repeated taps with TGF β1 levels examination. In case of persisting hydrocephalus MRI was performed. In 16 patients with proved (en)
Title	Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus (en)
skos:prefLabel	Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus (en)
skos:notation	RIV/00843989:_____/10:00100917!RIV11-MZ0-00843989
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Podešvová, Hana Nováčková, Ludmila Lipina, Radim Reguli, Štefan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Ostrava
http://linked.open...dnocenehoVysledku	284617
http://linked.open...ai/riv/idVysledku	RIV/00843989:_____/10:00100917
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	posthemorrhagic hydrocephalus; endoscopic third ventriculostomy; transforming growth factor ß1; premature infants (en)
http://linked.open.../riv/klicoveSlovo	premature infants endoscopic third ventriculostomy posthemorrhagic hydrocephalus transforming growth factor ß1
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[1A2395F2CB64]
http://linked.open...i/riv/nazevZdroje	Child's nervous system
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	26
http://linked.open...iv/tvurceVysledku	Nováčková, Ludmila Lipina, Radim Reguli, Štefan Podešvová, Hana Brichtová, E.
http://linked.open...ain/vavai/riv/wos	000274500800009
issn	0256-7040
number of pages	9 (xsd:int)

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