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Description
| - Therapy of posthemorrhagic hydrocephalus (PHH) by using ventriculo-peritoneal drainage bears considerable rate of complications and remains a challenge in premature newborns. The role of endoscopic third ventriculostomy (ETV) in these patients is unclear, through obstruction is proved in some patients with PHH.TGF β 1 release into the CSF in time of primary bleeding is suggested as one of possible pathophysiologic reasons of PHH formation. Relation between TGF β1 levels and ETV success rate has not been reported yet. The aim of our study is to detect group of patients, according to the levels of TGF β1, who have MRI proved obstruction hydrocefalus without participation of hyporesorption – so that we can expect success of ETV. MethodsWe followed 29 premature newborns with PHH during 2005-2007, all of them treated by Ommaya reservoir implantation and repeated taps with TGF β1 levels examination. In case of persisting hydrocephalus MRI was performed. In 16 patients with proved
- Therapy of posthemorrhagic hydrocephalus (PHH) by using ventriculo-peritoneal drainage bears considerable rate of complications and remains a challenge in premature newborns. The role of endoscopic third ventriculostomy (ETV) in these patients is unclear, through obstruction is proved in some patients with PHH.TGF β 1 release into the CSF in time of primary bleeding is suggested as one of possible pathophysiologic reasons of PHH formation. Relation between TGF β1 levels and ETV success rate has not been reported yet. The aim of our study is to detect group of patients, according to the levels of TGF β1, who have MRI proved obstruction hydrocefalus without participation of hyporesorption – so that we can expect success of ETV. MethodsWe followed 29 premature newborns with PHH during 2005-2007, all of them treated by Ommaya reservoir implantation and repeated taps with TGF β1 levels examination. In case of persisting hydrocephalus MRI was performed. In 16 patients with proved (en)
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Title
| - Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus
- Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus (en)
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skos:prefLabel
| - Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus
- Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus (en)
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skos:notation
| - RIV/00843989:_____/10:00100917!RIV11-MZ0-00843989
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00843989:_____/10:00100917
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - posthemorrhagic hydrocephalus; endoscopic third ventriculostomy; transforming growth factor ß1; premature infants (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Nováčková, Ludmila
- Lipina, Radim
- Reguli, Štefan
- Podešvová, Hana
- Brichtová, E.
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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