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rdf:type
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Description
| - Summary: A total 37 patients suffering from end stage-IV Fontaine (CLI and diabetic foot) with an ulcerated limb in whom all previous thera- peutic strategies failed (e.g. surgical revascularization and endovascular repair) were selected and underwent local transplantation of Autolo- gous Bone Marrow Stem Cells (ABMSCs). The efficacy/safety of this therapy was assessed by using several endpoints such as (a) prevention of amputation, (b) wound healing and (c) degree of angiogenesis. In order to assess the limb ischemia and hypoxia the several tests and measure- ments were performed pre- and post transplantation at a variety of time intervals. The measurements include: TP-toe pressure measurements (by Periflux 5000 Laser Doppler and Oxymetry system), SPP-skin perfusion pressure, ABI-ankle brachial index, LDP-Laser Doppler baseline and heat perfusion assessment, TcpO2 without and with O2 provocation inhalation test. In addition, a battery of biochemical and hemato- logical tests of periph
- Summary: A total 37 patients suffering from end stage-IV Fontaine (CLI and diabetic foot) with an ulcerated limb in whom all previous thera- peutic strategies failed (e.g. surgical revascularization and endovascular repair) were selected and underwent local transplantation of Autolo- gous Bone Marrow Stem Cells (ABMSCs). The efficacy/safety of this therapy was assessed by using several endpoints such as (a) prevention of amputation, (b) wound healing and (c) degree of angiogenesis. In order to assess the limb ischemia and hypoxia the several tests and measure- ments were performed pre- and post transplantation at a variety of time intervals. The measurements include: TP-toe pressure measurements (by Periflux 5000 Laser Doppler and Oxymetry system), SPP-skin perfusion pressure, ABI-ankle brachial index, LDP-Laser Doppler baseline and heat perfusion assessment, TcpO2 without and with O2 provocation inhalation test. In addition, a battery of biochemical and hemato- logical tests of periph (en)
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Title
| - Autologous Bone Marrow Stem Cell Transplantation in Patients with End-Stage Chronical Critical Limb Ischemia and Diabetic Foot
- Autologous Bone Marrow Stem Cell Transplantation in Patients with End-Stage Chronical Critical Limb Ischemia and Diabetic Foot (en)
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skos:prefLabel
| - Autologous Bone Marrow Stem Cell Transplantation in Patients with End-Stage Chronical Critical Limb Ischemia and Diabetic Foot
- Autologous Bone Marrow Stem Cell Transplantation in Patients with End-Stage Chronical Critical Limb Ischemia and Diabetic Foot (en)
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skos:notation
| - RIV/00843989:_____/09:00016075!RIV10-MZ0-00843989
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00843989:_____/09:00016075
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - critical limb ischemia; diabetic foot; bone marrow stem cells; transplantation (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Chmelová, Jana
- Gumulec, Jaromír
- Krajča, Jan
- Procházka, Václav
- Jonszta, Tomáš
- Czerný, Daniel
- Klement, Petr
- Klement, G. L.
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issn
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number of pages
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