About: PML protein expression in hereditary and sporadic breast cancer     Goto   Sponge   NotDistinct   Permalink

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Description
  • The aim of this study was to determine if there is any difference in PML protein expression in breast cancer of BRCA1 and BRCA2 gene mutation carriers compared to sporadic breast cancer and if the PML protein can be used as a prognostic marker. The PML protein was downregulated in approximately 30% of breast cancers cases. Downregulation of PML protein expression was significantly less frequent in BRCA1 mutation carriers compared to sporadic cases. No correlation was found between PML protein expression and any of the other clinical and laboratory characteristics.
  • The aim of this study was to determine if there is any difference in PML protein expression in breast cancer of BRCA1 and BRCA2 gene mutation carriers compared to sporadic breast cancer and if the PML protein can be used as a prognostic marker. The PML protein was downregulated in approximately 30% of breast cancers cases. Downregulation of PML protein expression was significantly less frequent in BRCA1 mutation carriers compared to sporadic cases. No correlation was found between PML protein expression and any of the other clinical and laboratory characteristics. (en)
Title
  • PML protein expression in hereditary and sporadic breast cancer
  • PML protein expression in hereditary and sporadic breast cancer (en)
skos:prefLabel
  • PML protein expression in hereditary and sporadic breast cancer
  • PML protein expression in hereditary and sporadic breast cancer (en)
skos:notation
  • RIV/00843989:_____/07:00014878!RIV12-MZ0-00843989
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V, Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika
  • 4
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http://linked.open...titaPredkladatele
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  • 441603
http://linked.open...ai/riv/idVysledku
  • RIV/00843989:_____/07:00014878
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  • PML protein; BRCA1 gene; BRCA2 gene; breast cancer (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • SK - Slovenská republika
http://linked.open...ontrolniKodProRIV
  • [A0E6D317BA72]
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  • Neoplasma
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http://linked.open...v/svazekPeriodika
  • 54
http://linked.open...iv/tvurceVysledku
  • Bouchal, J.
  • Zapletalová, J.
  • Prokop, Jiří
  • Foretová, L.
  • Kolář, Z.
  • Kubala, Otakar
  • Čuřík, Romuald
  • Plevová, P.
  • Navrátilová, M.
  • Fiurášková, M.
http://linked.open...ain/vavai/riv/wos
  • 000251196300001
http://linked.open...n/vavai/riv/zamer
issn
  • 0028-2685
number of pages
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