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rdf:type
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Description
| - Monocyte chemoattractant protein (MCP)-1 is the key chemokine in the process of atheroslerotic vascular inflammation. Examining already reported association between coronary artery disease (CAD) and the SNP A/G in the MCP-1 gene (position -2518), 139 Czech patients with CAD manifested as myocardial infarction (MI) and 359 unrelated healthy control (C) subjects were genotyped by PCR-SSP. Genotype and allele frequencies were not different in MI and C groups (allele G: MI, 20.5%; C, 23.8%, OR = 0.8, P > 0.05). No differences were detected when the patients were subdivided based on sex or the age of MI first occurrence. Further, no relationship was observed between circulating MCP-1 levels and carriage of the G allele. The data do not support a role for the MCP-1 -2518 single nucleotide polymorphism in susceptibility to CAD manifested by myocardial infarction
- Monocyte chemoattractant protein (MCP)-1 is the key chemokine in the process of atheroslerotic vascular inflammation. Examining already reported association between coronary artery disease (CAD) and the SNP A/G in the MCP-1 gene (position -2518), 139 Czech patients with CAD manifested as myocardial infarction (MI) and 359 unrelated healthy control (C) subjects were genotyped by PCR-SSP. Genotype and allele frequencies were not different in MI and C groups (allele G: MI, 20.5%; C, 23.8%, OR = 0.8, P > 0.05). No differences were detected when the patients were subdivided based on sex or the age of MI first occurrence. Further, no relationship was observed between circulating MCP-1 levels and carriage of the G allele. The data do not support a role for the MCP-1 -2518 single nucleotide polymorphism in susceptibility to CAD manifested by myocardial infarction (en)
- Protein MCP-1 je klíčovým chemokinem v procesu aterosklerotického zánětu. Studie ukazuje na vztah mezi kardiovaskulárním onemocněním a SNP A/G polymorfismem v genu (cs)
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Title
| - The MCP-1-2518 (A to G) single nucleotide polymorphism is not associated with myocardial infarction in the Czech population
- V české populaci není polymorfismus MCP-1-2518 (A/G) asociován s infarktem myokardu (cs)
- The MCP-1-2518 (A to G) single nucleotide polymorphism is not associated with myocardial infarction in the Czech population (en)
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skos:prefLabel
| - The MCP-1-2518 (A to G) single nucleotide polymorphism is not associated with myocardial infarction in the Czech population
- V české populaci není polymorfismus MCP-1-2518 (A/G) asociován s infarktem myokardu (cs)
- The MCP-1-2518 (A to G) single nucleotide polymorphism is not associated with myocardial infarction in the Czech population (en)
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skos:notation
| - RIV/00843989:_____/05:00100007!RIV09-MZ0-00843989
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00843989:_____/05:00100007
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - coronary-artery-disease; chemoattractant protein-1; gene; genotype (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - International Journal of Immunogenetics
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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