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Description
  • Two cases of adult testicular teratoma with shadow cell differentiation (SCD) similar to that seen commonly in pilomatrixoma are presented. The patients aged 21 and 27 years, and both tumors were limited to the testis. The differentiation of squamous epithelium toward shadow cells is well known in cutaneous pilomatrixoma and related lesions, some odontogenic tumors, craniopharyngeoma, and it was recently observed in several visceral carcinomas. In testicular location, SCD was so far described in benign dermoid cyst but not in teratoma, suggesting that the occurrence of shadow cells could help in differential diagnosis between these lesions. This is, however, not the case and the distinction of teratoma from dermoid cyst must be based on other morphological findings.
  • Two cases of adult testicular teratoma with shadow cell differentiation (SCD) similar to that seen commonly in pilomatrixoma are presented. The patients aged 21 and 27 years, and both tumors were limited to the testis. The differentiation of squamous epithelium toward shadow cells is well known in cutaneous pilomatrixoma and related lesions, some odontogenic tumors, craniopharyngeoma, and it was recently observed in several visceral carcinomas. In testicular location, SCD was so far described in benign dermoid cyst but not in teratoma, suggesting that the occurrence of shadow cells could help in differential diagnosis between these lesions. This is, however, not the case and the distinction of teratoma from dermoid cyst must be based on other morphological findings. (en)
  • Popsané jsou dva případy testikulárního teratomu s fokální %22shadow cell%22 diferenciací (SCD), která je jinak typická pro kožní pilomatrixom. Věk pacientů byl 21 a 27 let a oba tumory byly limitované na testis. SCD byla doposud známa v pilomatrixomu a jiných kožních lézích, odontogenních tumorech, kraniofaryngeomu a některých viscerálních adenokarcinomech. V testis byla popsaná jen v dermoidní cystě, zatímco v teratomu takové pozorování chybělo. Tento rozdíl mohl být potenciální pomocí při rozlišení mezi dermoidní cystou a teratomem s převahou zralých dermoidních struktur. Naše pozorování však tuto možnost negují a diferenciální diagnóza mezi oběma lézemi zůstává tak závislá na posouzení jiných změn (dermoidní cystu favorizuje makroskopicky cystický vzhled bez solidních části a histologicky chybí intratubulární neoplazie, atypie, mitotická aktivita a přítomnost nanejvýš minoritní non-dermoidní složky). (cs)
Title
  • Shadow cell differentiation in testicular teratomas. A report of two cases
  • Shadow cell differentiation in testicular teratomas. A report of two cases (en)
  • Diferenciace do stínových buněk (%22shadow cells%22) v teratomech varlat. Popis dvou případů. (cs)
skos:prefLabel
  • Shadow cell differentiation in testicular teratomas. A report of two cases
  • Shadow cell differentiation in testicular teratomas. A report of two cases (en)
  • Diferenciace do stínových buněk (%22shadow cells%22) v teratomech varlat. Popis dvou případů. (cs)
skos:notation
  • RIV/00843989:_____/05:00012368!RIV09-MZ0-00843989
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 542489
http://linked.open...ai/riv/idVysledku
  • RIV/00843989:_____/05:00012368
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • testis; teratoma; dermoid cyst; pilomatrixoma; shadow cell differentiation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [FF8E5DE566A9]
http://linked.open...i/riv/nazevZdroje
  • Česko-slovenská patologie a soudní lékařství
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 41
http://linked.open...iv/tvurceVysledku
  • Michal, M.
  • Zámečník, M.
  • Čuřík, Romuald
  • Mukenšnábl, P.
issn
  • 1210-7875
number of pages
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