About: Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma

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About: Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ncbi.nlm.nih.gov/pubmed/21699377
Description	The retrospective study evaluated the secondary clinical risk score at relapse, the prognostic significance of pre-transplant positron emission tomography (PET), and complete remission (CR) assessed by computed tomography (CT) after salvage chemotherapy before autologous stem cell transplant (ASCT) in 76 patients with relapsed/refractory Hodgkin lymphoma (HL). Median follow-up after ASCT was 23 months. Overall 11/20 PET-positive and 14/56 PET-negative patients relapsed after ASCT. In univariate analysis, only PET negativity before ASCT was significantly associated with better 2-year progression-free survival (PFS) and 2-year overall survival (OS). Other factors were not significant. In multivariate analysis, none of the evaluated factors were significant for PFS and OS. However, positive pre-transplant PET identified a population with worse PFS and OS at least in univariate analysis. The retrospective study evaluated the secondary clinical risk score at relapse, the prognostic significance of pre-transplant positron emission tomography (PET), and complete remission (CR) assessed by computed tomography (CT) after salvage chemotherapy before autologous stem cell transplant (ASCT) in 76 patients with relapsed/refractory Hodgkin lymphoma (HL). Median follow-up after ASCT was 23 months. Overall 11/20 PET-positive and 14/56 PET-negative patients relapsed after ASCT. In univariate analysis, only PET negativity before ASCT was significantly associated with better 2-year progression-free survival (PFS) and 2-year overall survival (OS). Other factors were not significant. In multivariate analysis, none of the evaluated factors were significant for PFS and OS. However, positive pre-transplant PET identified a population with worse PFS and OS at least in univariate analysis. (en)
Title	Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma (en)
skos:prefLabel	Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma (en)
skos:notation	RIV/00669806:_____/11:10107683!RIV12-MZ0-00669806
http://linked.open...avai/riv/aktivita	I N S V Z
http://linked.open...avai/riv/aktivity	I, N, S, V, Z(MSM0021620808)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Koza, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Plzeň
http://linked.open...dnocenehoVysledku	223186
http://linked.open...ai/riv/idVysledku	RIV/00669806:_____/11:10107683
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	analogous stem cell transplant; PET; Hodgkin lymphoma (en)
http://linked.open.../riv/klicoveSlovo	PET analogous stem cell transplant Hodgkin lymphoma
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[BDABF57FCD69]
http://linked.open...i/riv/nazevZdroje	Leukemia and Lymphoma
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	52
http://linked.open...iv/tvurceVysledku	Koza, Vladimír Kozák, Tomáš Marková, Jana Mayer, Jiří Mociková, Heidi Pytlík, Robert Trněný, Marek Žák, Pavel Král, Zdeněk Belada, David Steinerová, Kateřina Trnková, Marie
http://linked.open...ain/vavai/riv/wos	000294228100010
http://linked.open...n/vavai/riv/zamer	Molekulárně biologické, genetické a epigenetické aspekty vzniku a rozvoje modelových tumorů dospělého věku. Význam pro epidemiologii, časnou diagnostiku a léčbu
issn	1042-8194
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.3109/10428194.2011.573889

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