About: Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.hh.um.es/pdf/Vol_26/26_9/Kuroda-26-1215-1218-2011.pdf
Description	Acquired cystic disease (ACD)-associated renal cell carcinoma (RCC) is a recently established entity. In this article, we introduce the general view of this new entity. Macroscopically, the disease exclusively occurs in ACD and may arise as a dominant mass or non-dominant masses. Histologically, the tumor is characterized by a microcystic pattern, neoplastic cells with an eosinophilic or oncocytic cytoplasm and frequent intratumoral oxalate crystal deposition. Prominent nucleoli of tumor cells are often observed. Immunohistochemically, neoplastic cells are generally positive for AMACR but negative for cytokeratin 7. Ultrastructurally, neoplastic cells contain abundant mitochondria in the cytoplasm. Genetically, the gain of chromosomes 3, 7, 17 and abnormality of the sex chromosome were frequently observed in several studies. In conclusion, ACD-associated RCC may be widely recognized as a distinct entity in the near future because this tumor is morphologically and genetically different from other renal tumor entities that have been previously established. Acquired cystic disease (ACD)-associated renal cell carcinoma (RCC) is a recently established entity. In this article, we introduce the general view of this new entity. Macroscopically, the disease exclusively occurs in ACD and may arise as a dominant mass or non-dominant masses. Histologically, the tumor is characterized by a microcystic pattern, neoplastic cells with an eosinophilic or oncocytic cytoplasm and frequent intratumoral oxalate crystal deposition. Prominent nucleoli of tumor cells are often observed. Immunohistochemically, neoplastic cells are generally positive for AMACR but negative for cytokeratin 7. Ultrastructurally, neoplastic cells contain abundant mitochondria in the cytoplasm. Genetically, the gain of chromosomes 3, 7, 17 and abnormality of the sex chromosome were frequently observed in several studies. In conclusion, ACD-associated RCC may be widely recognized as a distinct entity in the near future because this tumor is morphologically and genetically different from other renal tumor entities that have been previously established. (en)
Title	Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects (en)
skos:prefLabel	Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects (en)
skos:notation	RIV/00669806:_____/11:10105749!RIV12-MZ0-00669806
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Michal, Michal Hes, Ondřej
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Plzeň
http://linked.open...dnocenehoVysledku	226915
http://linked.open...ai/riv/idVysledku	RIV/00669806:_____/11:10105749
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Sex chromosome; Chromosome 3; Oxalate crystals; Acquired cystic disease-associated renal cell carcinoma (en)
http://linked.open.../riv/klicoveSlovo	Chromosome 3 Oxalate crystals Sex chromosome Acquired cystic disease-associated renal cell carcinoma
http://linked.open...odStatuVydavatele	ES - Španělské království
http://linked.open...ontrolniKodProRIV	[AA1801D9C372]
http://linked.open...i/riv/nazevZdroje	Histology and Histopathology
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	26
http://linked.open...iv/tvurceVysledku	Brunelli, Matteo Hes, Ondřej Kakehi, Yoshiyuki Kuroda, Naoto Lee, Gang-Hong Martignoni, Guido Michal, Michal Mikami, Shuji Ohe, Chisato Shuin, Taro Sato, Yasuharu Yoshino, Tadashi
http://linked.open...ain/vavai/riv/wos	000292683600012
issn	0213-3911
number of pages	4 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software