About: Study of metallothionein–quantum dots interactions

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Nanoparticles have gained increasing interest in medical and in vivo applications. Metallothionein (MT)is well known as a maintainer of metal ions balance in intracellular space. This is due to high affinityof this protein to any reactive species including metals and reactive oxygen species. The purpose ofthis study was to determine the metallothionein–quantum dots interactions that were investigated byspectral and electrochemical techniques. CuS, CdS, PbS, and CdTe quantum dots (QDs) were analysed.The highest intensity was shown for CdTe, than for CdS measured by fluorescence. These results weresupported by statistical analysis and considered as significant. Further, these interactions were analysedusing gel electrophoresis, where MT aggregates forming after interactions with QDs were detected. Usingdifferential pulse voltammetry Brdicka reaction, QDs and MT were studied. This method allowed us toconfirm spectral results and, moreover, to observe the changes in MT structure causing new voltammetric Nanoparticles have gained increasing interest in medical and in vivo applications. Metallothionein (MT)is well known as a maintainer of metal ions balance in intracellular space. This is due to high affinityof this protein to any reactive species including metals and reactive oxygen species. The purpose ofthis study was to determine the metallothionein–quantum dots interactions that were investigated byspectral and electrochemical techniques. CuS, CdS, PbS, and CdTe quantum dots (QDs) were analysed.The highest intensity was shown for CdTe, than for CdS measured by fluorescence. These results weresupported by statistical analysis and considered as significant. Further, these interactions were analysedusing gel electrophoresis, where MT aggregates forming after interactions with QDs were detected. Usingdifferential pulse voltammetry Brdicka reaction, QDs and MT were studied. This method allowed us toconfirm spectral results and, moreover, to observe the changes in MT structure causing new voltammetric (en)
Title	Study of metallothionein–quantum dots interactions Study of metallothionein–quantum dots interactions (en)
skos:prefLabel	Study of metallothionein–quantum dots interactions Study of metallothionein–quantum dots interactions (en)
skos:notation	RIV/00216305:26620/14:PU112619!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita	O P
http://linked.open...avai/riv/aktivity	O, P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Křížková, Soňa Trnková, Libuše Hynek, David Adam, Vojtěch Kizek, René Tmejová, Kateřina Kopel, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	48299
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/14:PU112619
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Electrochemical detection, Metallothionein, Quantum dots, Interaction (en)
http://linked.open.../riv/klicoveSlovo	Metallothionein Interaction Electrochemical detection Quantum dots
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[ABD2D2D68522]
http://linked.open...i/riv/nazevZdroje	Colloids and Surfaces B: Biointerfaces
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	117
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Hynek, David Kizek, René Křížková, Soňa Trnková, Libuše Tmejová, Kateřina Kopel, Pavel
http://linked.open...ain/vavai/riv/wos	000336018700070
issn	0927-7765
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	26620

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