About: Chemical modification and characterization of hydrogels from natural polysaccharide Gum Karaya

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Gum Karaya (GK) is a natural gum exudate of Sterculia urens tree. GK is a partially acetylated, insoluble and anionic polysaccharide. It is obtained as calcium and magnesium salt and contains of ß-D-galactose, L-rhamnose, ß-D-glucuronic acid and D-galacturonic acid. The swelling behaviour of GK is caused by the presence of the acetyl groups and multivalent ions in the GK structure. The present study deals with purification and chemical modification of GK to developed soluble material by alkali treatment for subsequent potential use in medicine (e.g. hydrogels for soft tissue regeneration of drug delivery systems). Conditions of modification reaction such as type of hydroxide, concentration of GK dispersion and time of reaction were optimized and mechanism of the reaction was proposed. Original GK and modified GK samples were studied by SEM, FTIR, TGA, DSC, ICP OES, GPC, NMR and rheological studies. The linear viscoelastic region was determined by rheological measurements. The effect of NaCl on visco Gum Karaya (GK) is a natural gum exudate of Sterculia urens tree. GK is a partially acetylated, insoluble and anionic polysaccharide. It is obtained as calcium and magnesium salt and contains of ß-D-galactose, L-rhamnose, ß-D-glucuronic acid and D-galacturonic acid. The swelling behaviour of GK is caused by the presence of the acetyl groups and multivalent ions in the GK structure. The present study deals with purification and chemical modification of GK to developed soluble material by alkali treatment for subsequent potential use in medicine (e.g. hydrogels for soft tissue regeneration of drug delivery systems). Conditions of modification reaction such as type of hydroxide, concentration of GK dispersion and time of reaction were optimized and mechanism of the reaction was proposed. Original GK and modified GK samples were studied by SEM, FTIR, TGA, DSC, ICP OES, GPC, NMR and rheological studies. The linear viscoelastic region was determined by rheological measurements. The effect of NaCl on visco (en)
Title	Chemical modification and characterization of hydrogels from natural polysaccharide Gum Karaya Chemical modification and characterization of hydrogels from natural polysaccharide Gum Karaya (en)
skos:prefLabel	Chemical modification and characterization of hydrogels from natural polysaccharide Gum Karaya Chemical modification and characterization of hydrogels from natural polysaccharide Gum Karaya (en)
skos:notation	RIV/00216305:26620/14:PU112482!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Vojtová, Lucy Jančář, Josef Chamradová, Ivana
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	7086
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/14:PU112482
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	natural gum, polysaccharide, gum karaya, chemical modification, characterization, solubility (en)
http://linked.open.../riv/klicoveSlovo	chemical modification characterization polysaccharide natural gum solubility gum karaya
http://linked.open...ontrolniKodProRIV	[3B85CC4C5849]
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Jančář, Josef Vojtová, Lucy Chamradová, Ivana Poštulková, Hana
http://localhost/t...ganizacniJednotka	26620

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