About: Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of this study was to investigate the interaction between lead ions and ethylenediaminetetraacetic acid (EDTA) in plasma. EDTA is widely used in medicine as anticoagulant agent. Understanding of the influence of EDTA on the electrochemical lead ions determination is very suitable for the determination of lead ions at patients with increased metals levels in body fluids. Further, the changes of metal ions levels (Zn, Cd, Pb and Cu) were monitored in the blood plasma of child patients treated for various oncological diseases. Electrochemical method differential pulse voltammetry with fully automated system and atomic absorption spectrometry was used for determination of the metal ions. It was found an increased amount of metal ions in the blood plasma of patients suffering from cancer disease in comparison with physiological values in healthy people. In these patients there was also found that they have higher levels of metallothionein and the ratio of GSH/GSSG was reduced. These results suggest The aim of this study was to investigate the interaction between lead ions and ethylenediaminetetraacetic acid (EDTA) in plasma. EDTA is widely used in medicine as anticoagulant agent. Understanding of the influence of EDTA on the electrochemical lead ions determination is very suitable for the determination of lead ions at patients with increased metals levels in body fluids. Further, the changes of metal ions levels (Zn, Cd, Pb and Cu) were monitored in the blood plasma of child patients treated for various oncological diseases. Electrochemical method differential pulse voltammetry with fully automated system and atomic absorption spectrometry was used for determination of the metal ions. It was found an increased amount of metal ions in the blood plasma of patients suffering from cancer disease in comparison with physiological values in healthy people. In these patients there was also found that they have higher levels of metallothionein and the ratio of GSH/GSSG was reduced. These results suggest (en)
Title	Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry (en)
skos:prefLabel	Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry (en)
skos:notation	RIV/00216305:26620/14:PU111696!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita	I O P
http://linked.open...avai/riv/aktivity	I, O, P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kenšová, Renata Kynický, Jindřich Hynek, David Adam, Vojtěch Hubálek, Jaromír Kizek, René Novotná, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	10792
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/14:PU111696
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Metals, Electrochemical Analysis, Plasma, EDTA, Interaction, Oncological Diseases (en)
http://linked.open.../riv/klicoveSlovo	Interaction Electrochemical Analysis EDTA Plasma Metals Oncological Diseases
http://linked.open...odStatuVydavatele	RS - Srbská republika
http://linked.open...ontrolniKodProRIV	[7230111E321B]
http://linked.open...i/riv/nazevZdroje	INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
http://linked.open...in/vavai/riv/obor	JU
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	9
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Eckschlager, Tomáš Hubálek, Jaromír Hynek, David Kizek, René Kynický, Jindřich Novotná, Marie Kenšová, Renáta
issn	1452-3981
number of pages	17 (xsd:int)
http://localhost/t...ganizacniJednotka	26620

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