About: Cyclopropylamine plasma polymers deposited onto quartz crystal microbalance for biosensing application

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Biosensors have been extensively developed and applied for biomedical and environmental studies. Although there are many different types of biosensing techniques, all these methods require immobilization of biomolecules. Therefore, this is a critical issue in the development of any sort of biosensor affecting its operational properties. In this work, we address this critical issue by employing cyclopropylamine plasma polymerization to deposit stable amine thin films on the surface of quartz crystal microbalance (QCM) biosensors. The antibody specific to human serum albumin (anti-HSA) is attached to the QCM surface via cross-linkage obtained by intermediate reaction with glutaraldehyde. All steps of the bio-immobilization are controlled by XPS and FTIR to characterize surface and layer (bulk) chemistry. The results obtained with the antibody linked through the CPA plasma-polymerized layer are comparable with the results obtained previously when the same antibody AL-01 was linked to the surface using th Biosensors have been extensively developed and applied for biomedical and environmental studies. Although there are many different types of biosensing techniques, all these methods require immobilization of biomolecules. Therefore, this is a critical issue in the development of any sort of biosensor affecting its operational properties. In this work, we address this critical issue by employing cyclopropylamine plasma polymerization to deposit stable amine thin films on the surface of quartz crystal microbalance (QCM) biosensors. The antibody specific to human serum albumin (anti-HSA) is attached to the QCM surface via cross-linkage obtained by intermediate reaction with glutaraldehyde. All steps of the bio-immobilization are controlled by XPS and FTIR to characterize surface and layer (bulk) chemistry. The results obtained with the antibody linked through the CPA plasma-polymerized layer are comparable with the results obtained previously when the same antibody AL-01 was linked to the surface using th (en)
Title	Cyclopropylamine plasma polymers deposited onto quartz crystal microbalance for biosensing application Cyclopropylamine plasma polymers deposited onto quartz crystal microbalance for biosensing application (en)
skos:prefLabel	Cyclopropylamine plasma polymers deposited onto quartz crystal microbalance for biosensing application Cyclopropylamine plasma polymers deposited onto quartz crystal microbalance for biosensing application (en)
skos:notation	RIV/00216305:26620/14:PU111671!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Polčák, Josef Čechal, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	9517
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/14:PU111671
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	amine plasma, biosensors, polymers, quartz crystal microbalance, X-ray photoelectron spectroscopy (en)
http://linked.open.../riv/klicoveSlovo	polymers X-ray photoelectron spectroscopy biosensors quartz crystal microbalance amine plasma
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[7018609AAD01]
http://linked.open...i/riv/nazevZdroje	physica status solidi (a)
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	211
http://linked.open...iv/tvurceVysledku	Eliáš, Marek Nečas, David Zajíčková, Lenka Čechal, Jan Skládal, Petr Polčák, Josef Manakhov, Anton
issn	1862-6300
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	26620

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