About: Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery     Goto   Sponge   NotDistinct   Permalink

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Description
  • Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and expensive. In this study, we describe an easy and inexpensive method to create 3D hydroxyapatite structure containing porous hollow fibers via microtemplating. The fibers which are assembled into 3D scaffold and sintered, contain asymmetric membrane walls with flux suitable for nutrient delivery. These hollow fibers have good mesenchymal stem cell adhesion showing that the presented method has no negative influence on cell cytocompatibility. The proposed straightforward method for building 3D structures containing porous hollow fibers for nutritions can be suitable for in vitro bioreactors studies as well as for production tissue engineered or in vivo prepared bone grafts.
  • Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and expensive. In this study, we describe an easy and inexpensive method to create 3D hydroxyapatite structure containing porous hollow fibers via microtemplating. The fibers which are assembled into 3D scaffold and sintered, contain asymmetric membrane walls with flux suitable for nutrient delivery. These hollow fibers have good mesenchymal stem cell adhesion showing that the presented method has no negative influence on cell cytocompatibility. The proposed straightforward method for building 3D structures containing porous hollow fibers for nutritions can be suitable for in vitro bioreactors studies as well as for production tissue engineered or in vivo prepared bone grafts. (en)
Title
  • Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery
  • Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery (en)
skos:prefLabel
  • Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery
  • Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery (en)
skos:notation
  • RIV/00216305:26620/14:PU111294!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika
  • 9
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 16311
http://linked.open...ai/riv/idVysledku
  • RIV/00216305:26620/14:PU111294
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Sintering, Membrane, Hydroxyapatite, Microtemplating, Cell adhesion (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [2BBDB5A44452]
http://linked.open...i/riv/nazevZdroje
  • Ceramics International
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 40
http://linked.open...iv/tvurceVysledku
  • Salamon, David
  • Dutczak, Szymon M.
  • Stamatialis, Dimitrios F.
  • Teixeira, Sandra
http://linked.open...ain/vavai/riv/wos
  • 000341343300032
issn
  • 0272-8842
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.ceramint.2014.06.071
http://localhost/t...ganizacniJednotka
  • 26620
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