About: Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones

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About: Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The principal purpose of the present study is to synthesize and investigate the antimicrobial and antifungal activities of new 1, 3-selenazole derivatives having phthalazin-1(2H)-one moieties. A multi-step reaction route was developed to synthesize a several of targeted derivatives starting from 4-alkyl/aryl-phthalazin-1(2H)-one and 2-chloro-N-phenylacetamide. The structures of the synthesized compounds were confirmed by 1HNMR, 13CNMR, MS, IR spectroscopy and by elemental analysis. The antimicrobial and antifungal activities of all derivatives against four species of bacteria and two species of fungi were investigated. The antimicrobial and antifungal activity was determined in the extracts using disk diffusion method. Amoxicillin and Ketoconazole were used as standard drugs for the bacteria and fungi, respectively. The principal purpose of the present study is to synthesize and investigate the antimicrobial and antifungal activities of new 1, 3-selenazole derivatives having phthalazin-1(2H)-one moieties. A multi-step reaction route was developed to synthesize a several of targeted derivatives starting from 4-alkyl/aryl-phthalazin-1(2H)-one and 2-chloro-N-phenylacetamide. The structures of the synthesized compounds were confirmed by 1HNMR, 13CNMR, MS, IR spectroscopy and by elemental analysis. The antimicrobial and antifungal activities of all derivatives against four species of bacteria and two species of fungi were investigated. The antimicrobial and antifungal activity was determined in the extracts using disk diffusion method. Amoxicillin and Ketoconazole were used as standard drugs for the bacteria and fungi, respectively. (en)
Title	Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones (en)
skos:prefLabel	Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones (en)
skos:notation	RIV/00216305:26620/13:PU108211!RIV14-MSM-26620___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(EE2.3.30.0005)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Abdel-Lattif, Abdel-Mohsan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	104539
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/13:PU108211
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Selenium, phthalazin-1(2H)-one, antimicrobial activity (en)
http://linked.open.../riv/klicoveSlovo	phthalazin-1(2H)-one antimicrobial activity Selenium
http://linked.open...odStatuVydavatele	CN - Čínská lidová republika
http://linked.open...ontrolniKodProRIV	[8E3E1E60876D]
http://linked.open...i/riv/nazevZdroje	Life Science Journal
http://linked.open...in/vavai/riv/obor	JU
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology Support of Interdisciplinary Excellence Research Teams Establishment at BUT
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	10
http://linked.open...iv/tvurceVysledku	Almonasy, Numan Abdel-Lattif, Abdel-Mohsan Al-Deyab, Salem S. El-Shamy, Ibrahim E. Fouda, Moustafa M.D. El-Hashash, Maher A.
issn	1097-8135
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	26620

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